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Journal of Infectious Diseases & Therapy |ISSN: 2332-0877 | Volume 6
June 25-26, 2018 | Vancouver, Canada
3
rd
International Conference on
2
nd
International Conference on
Infection, Disease Control and Prevention
Microbial Pathogenesis & Infectious Diseases
&
Vitamin D deficiency in hepatitis C virus infection: What's old? What's new?
Chao-Nan Jin
Zhejiang University, China
I
n the last few years, a growing body of clinical evidence has highlighted the risk of vitamin D deficiency in chronic hepatitis C
patients and that vitamin D levels are associated with the course of hepatitis C virus infection, adverse effects and treatment response
to peginterferon/ribavirin. Recently, studies have found that vitamin D status is related to drug resistance and increased risk of
infection in patients with liver cirrhosis. Vitamin D-related gene polymorphisms have been found to explain the interactions between
vitamin D deficiency and HCV infection, offering a new perspective to understand current problems such as the development of
insulin resistance and racial differences in sustained virological response. Studies have been conducted to determine whether vitamin
D supplementation as an adjuvant yields a better result compared to traditional HCV treatment. Here, we provide a brief review of
the past and present knowledge of vitamin D in HCV infection.
J Infect Dis Ther 2018, Volume 6
DOI: 10.4172/2332-0877-C2-042