7 / 15
Page 47
Notes:
conferenceseries
.com
Volume 7, Issue 5 (Suppl)
J Gastrointest Dig Syst, an open access journal
ISSN:2161-069X
Gastroenterology 2017
November 13-14, 2017
November 13-14, 2017 | Las Vegas, USA
13
th
International Conference on
Clinical Gastroenterology, Hepatology and Endoscopy
Hepatitis E virus in patients with HIV infection
Turdieva Nigora
Ministry of Health and Social Protection, Tajikistan
T
he aim of the study was to document the incidence of chronic HEV coinfection in patients with HIV infection and to determine
the anti-HEV seroprevalence and compare it with that of a control population. Total of 246 patients with HIV infectionand
94 control subjects were tested for HEV using an immunoassay for anti-HEV IgG and were tested for anti-HCV and HBsAg.
Demographic, lifestyle and laboratory data were prospectively collected on each patient with HIV infection. The prevalence of HEV
IgG seropositivity in the 246 HIV infection is shown that in the male group, 19.1% (27/141) were positive as against 29.5% (31/105)
in the female group. In addition, subjects over 40 years of age had a higher prevalence of HEV IgG seropositivity than those aged
>40 years (OR=2.780, P<0.01). There was no difference in anti-HEV IgG seroprevalence between the HIV-infected patients and
controls. The only risk factor predictive of anti-HEV seropositivity was the consumption of raw/undercooked meat or liver; sexual
risk factors were unrelated. We also examined the relationship between HEV infection and HBV or HCV coinfection in patients with
HIV infection. The results showed no significant difference in HBsAg positive status (6.8% vs 7.4%) and HCV positive status (5.1%
vs 6.3%) between HEV IgG positive and negative patients with HIV infection. No statistically significant association between HEV
seropositivity and HBV and HCV infection was observed. So, Anti-HEV seroprevalence is similar in controls and patients with HIV
infection. Risk factor analysis suggests that HEV is not transmitted sexually. No statistically significant association between HEV
seropositivity and HBV and HCV infection was observed.
Biography
Turdieva Nigora at the age of 37 years graduated from Instutute of Gastroenterology of the Republic of Tajikistan. She works at the Department of Virology, Institute of
Gastroenterology of the Republic of Tajikistan. She has published more than 5 papers in reputed journals.
dustovsamad@gmail.comTurdieva Nigora, J Gastrointest Dig Syst 2017, 7:5 (Suppl)
DOI: 10.4172/2161-069X-C1-056