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Volume 7, Issue 7 (Suppl)
J Gastrointest Dig Syst
ISSN: 2161-069X JGDS, an open access journal
Gastroenterologists 2017
December 14-15, 2017
December 14-15, 2017 Dubai, UAE
11
th
World
Gastroenterologists Summit
Pediatric GI motility: Clinical updates
Anil Darbari
Children’s National Health System, USA
T
he field of pediatric GI motility has seen several advances over the recent past. Updates in Pathophysiology: As the field
of neuro-gastroenterology has advanced, knowledge about the pathophysiology at the cellular, tissue, organ and torso
levels has all advanced. While the Enteric Nervous System (ENS) has been studied for decades, advances allow us better
understanding of the intrinsic primary afferent neurons (IPANs), interneurons, motor neurons and the intestinofugal neurons.
There is better understanding of the interstitial cells of Cajal (ICC) as well as the extrinsic control of the ENS and of the
sensation of the gut. Updates in GI motility studies: Various modalities for assessing GI motility have been utilized. From
radiological testing of scintigraphy, radiopaque markers and contrast studies, there have been advances with the use of MRI
and fMRI studies to evaluate how intestines move. Gastroenterologists have also paid much attention to this field in the 21
st
century. The use of manometry has advanced tremendously with the advent of high-resolution manometry (HRM), high
resolution impedance manometry (HRIM) and 3D HRM. Sleeve Manometry and EndoFLIP have changed our understanding
of reflux parameters. With the advent of the wireless capsule, transit times and other motility parameters can be studied non-
invasively. Updates in therapies for GI motility disorders: Newer drugs continue to advance the field of neuro-gastrointestinal
pharmacological therapy. Endoscopic therapy has shown tremendous progress with procedures such as endoscopic dilatation,
injection of botulinum toxin to the various sphincters and the advent of endoscopic procedures such as Per Oral Endoscopic
Myotomy (POEM). Surgical therapy techniques continue to be refined progressively and used for primary surgical procedures
such as minimally invasive surgery (MIS), laparoscopy and surgical resections. New therapeutic techniques such as gastric
electric stimulation (GES), sacral nerve stimulators as well as the prospect of stem cell transplant continue to keep the horizon
of GI motility disorders bright.
ADarbari@childrensnational.orgJ Gastrointest Dig Syst 2017, 7:7 (Suppl)
DOI: 10.4172/2161-069X-C1-062