euro-obesity-2016_posters-accepted-abstracts

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Volume 6, Issue 8(Suppl) J Obes Weight Loss Ther 2016
ISSN: 2165-7904 JOWT, an open access journal
Page 48
Notes:
Euro Obesity 2016
October 10-12, 2016
conferenceseries.com
7th Obesity & Endocrinology
Specialists Congress
October 10-12, 2016 Manchester, UK
Decreased deceleration capacity of rate and heart rate deceleration runs in patients suffering from type
2 diabetes mellitus with essential hypertension
Xing De Wang, Li Zhou, Chaoyu Zhu, Zhong Chen and Li Wei
Sixth People’s Hospital - Shanghai Jiao Tong University, China
This study aims to investigate the changes of deceleration capacity of rate (DC) and heart rate deceleration runs (DRs) in patients
suffering from type 2 diabetes mellitus (T2DM) with essential hypertension and to explore the correlation between them and
insulin resistance (IR). Fifty cases of T2DM and 95 cases of T2DM with essential hypertension as the experimental group, 50 cases
of normal physical examination as a control group were recruited. The related biochemical and metabolic index of 3 group patients
were measured; all patients were monitored with 24h Holter. DC, DRs and heart rate variability and other relevant indexes were
determined, the index changes of 3 groups were compared. Results showed that (1) T2DM and T2DM + HT group of DC, SDNN,
rMSSD, DR2, DR4, DR8 were decreased significantly than that of control group (P<0.05 and 0.001); (2) compared with T2DM
group, DC of T2DM + HT group also decreased significantly (P<0.05); (3) in T2DM and T2DM + HT group, DC and DR2, DR4,
DR8, SDNN, RMSSD was significantly positive correlation (P<0.0001 respectively), and significantly negative correlated to the FBG,
HbA1c, IR (P were 0.0196, 0.0013, <0.0001 respectively); (4) in T2DM and T2DM + HT group, IR and DC, DR 2, DR 4, DR8, SDNN was
significantly negative correlation (P were<0.0001, 0.0014, 0.0019, 0.0216, 0.0006, respectively), was significantly positive correlated
with AC, HbA1c (P were 0.0004 and 0.0003, respectively). In summary, in T2DMwith essential hypertension patients, the autonomic
function was damaged with IR, the DC and DRs detection can be used to assess cardiac autonomic function.
Biography
Xing De Wang graduated from Shanghai Second Medical University and Post-doctoral studies from Shanghai Jiao Tong University Affiliated Sixth People’s Hospital - East
Campus. He has published more than 20 papers in reputed journals and his major research interests were the non-invasive diagnosis of heart disease and complications
of other diseases, such as COPD and diabetes.
Xing De Wang et al., J Obes Weight Loss Ther 2016, 6:8(Suppl)