euro-obesity-2016_posters-accepted-abstracts

3 / 16

Volume 6, Issue 8(Suppl) J Obes Weight Loss Ther 2016
ISSN: 2165-7904 JOWT, an open access journal
Page 46
Notes:
Euro Obesity 2016
October 10-12, 2016
conferenceseries.com
7th Obesity & Endocrinology
Specialists Congress
October 10-12, 2016 Manchester, UK
Carotid intima-media thickness in patients with type 2 diabetes and the metabolic syndrome related factors
Wei Li, LiJie, Xiao YuanYuan, Zhu Chao Yu and Jia Weiping
Shanghai Jiao Tong University, China
Objective: To evaluate the relationship between carotid intima-media thickness (IMT) and metabolic syndrome (MS) with its
components in type 2 diabetes mellitus (T2DM) patients.
Methods: A random cluster sampling was conducted in 1884 employees of T2DM. All the subjects were divided into 2 groups
according to the IMT levels, control group: IMT<0.90 mm (n=1083) and IMT increased group: IMT≥0.90 mm (n=801). The risk
factors of metabolic syndrome (MS) in T2DM subjects with IMT were investigated.
Results: Compared with the control group, age, BMI, duration of diabetes mellitus, waist circumference (WC), hip circumference
(Hip), SBP (systolic blood pressure), LDL and lnCRP (log C-reactive protein, lnCRP) were significantly higher in the IMT increased
group (p<0.05). Multifactor logistic regression analysis demonstrated that age≥40 years, Duration≥10 years, BMI≥24 kg/m2, WC≥95
cm, Hip≥101 cm, LDL≥3.31mmol/L, lnCRP≥2.34mg/L and hypertension (HTN) were independent risk factors of the IMT thickening
in T2DM patients. Clustering analysis revealed that several metabolic syndrome (MS) components have a significant correlation with
different levels of IMT and there is a dose-response relationship between them (χ2=6.0~30.66, P<0.001).
Conclusion: MS related components are IMT thickening independent risk factors in T2DM patients. HDL is a protective factor
which can postpone the thickening of IMT. All of these indicating that it could be an effective method to prevent the carotid artery
atherosclerosis and delay diabetic macrovasculopathy by controlling obesity, blood pressure, blood lipid and carotid ultrasound
detection examination.
Biography
Wei Li is a Chief Physician, and Doctor Tutor of Shanghai Jiaotong University School of Medicine. She is a Member of the Endocrine and Metabolic branch of Shanghai
Medical Association. In 1985, he graduated from Xi’an Jiao Tong University School of Medicine. She published 70 papers in core journals, including 15 SCI journals. She is
an Editorial Board Member of Chinese Journal of Clinicians and Chinese Medical Science journal.
Wei Li et al., J Obes Weight Loss Ther 2016, 6:8(Suppl)