euro-obesity-2016_posters-accepted-abstracts

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Volume 6, Issue 8(Suppl) J Obes Weight Loss Ther 2016
ISSN: 2165-7904 JOWT, an open access journal
Page 47
Notes:
Euro Obesity 2016
October 10-12, 2016
conferenceseries.com
7th Obesity & Endocrinology
Specialists Congress
October 10-12, 2016 Manchester, UK
Biometry investigation of the ocular anterior segment in type 2 diabetes
Yan Liang, Jia Li Li, Li Wen, Mu Jing, Li Shi Wei and Wei Rong
Sixth People’s Hospital - Shanghai Jiao Tong University, China
Objective: To analyze the biometry parameters of the ocular anterior segment in type 2 diabetic mellitus (DM).
Methods: This is an observational cross-sectional study. 144 cases 285 eyes of DM patients’group age from 40 to 80 were collected
during Mar. to Nov. 2015 and non-contact optical biometry measurement (Lenstar LS900) was conducted with central corneal
thickness (CCT), white to white (WTW), anterior chamber depth (ACD), lens thickness (LT) and axial length (AL), and lens position
(LP), as well as chamber crowd ratio (CCR) were calculated. Data were compared with the counterpart of non-DM cataract patients
group and Wilcoxon Rank Sun Tests were employed to analyze the biometric differences between the 2 groups.
Results: Compared with the Non-DM cataract group, the average CCT of DM group was 533.64±33.29 nm vs. 527.08±31.61 nm
(χ2=6.4864, P=0.0109). WTW 11.54±0.51 mm vs. 11.42±0.63 mm (χ2=5.7074P=0.0169). ACD 2.50±0.32 mm vs. 2.61±0.43 mm
(χ2=12.7723, P=0.0004). LT was 4.52±0.32 mm vs. 4.31±0.45 mm (χ2=44.8900, P<0.0001). LP was 4.77±0.25 mm vs. 4.77±0.33
mm (χ2=0.0731, P=0.7869). CCR1 was 84±0.35 vs. 1.72±0.47 (χ2=29.6598, P<0.0001). ACD+LT was 7.02±0.28 nm vs. 6.92±0.37
nm (χ2=21.6796, P<0.0001). LT/AL was 0.30±0.01 vs. 0.28±0.02 (χ2=60.5197, P<0.0001). (ACD+LT)/AL 0.30±0.01 vs. 0.28±0.02
(χ2=68.3243, P <0.0001).
Conclusions: Hyperglycemia may lead to the corneal stromal and sub-basal neuropathy in type 2 DM patients. Alterations of the
ocular biometry parameters in such group may also lead to be more “crowed” of their anterior segments which herald that they may
be more susceptible to angle-closing.
Biography
Yan Liang obtained Doctor of Medicine (MD) degree from Johannes-Gutenberg University Mainz, Germany and is currently the Director of the Department of Ophthalmology,
Shanghai Jiao Tong University, Sixth People’s Hospital, East campus, Shanghai, China.
Yan Liang et al., J Obes Weight Loss Ther 2016, 6:8(Suppl)