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Volume 7, Issue 3(Suppl)
J Biotechnol Biomater, an open access journal
ISSN: 2155-952X
Euro Biotechnology 2017
September 25-27, 2017
17
th
EURO BIOTECHNOLOGY CONGRESS
September 25-27, 2017 Berlin, Germany
Production of biopolymers by bacterial cells
Ilona Jonuškiene
Kaunas University of Technology, Lithuania
I
n recent years,microorganism-basedbiopolymers have shownpromise as nontoxic, biodegradable andbiocompatiblenanomaterials.
Polysaccharide-based biopolymers have emerged as the most promising drug carriers for achieving prolonged circulation time,
reducing drug toxicity and protecting them from enzymatic degradation, enhancing antitumor capacity and controlling drug release.
The main objective of the present study is to investigate the different media composition for
Xanthomonas campestris
and
Azotobacter
vinelandii
growth and to select optimal conditions for purification of xanthan gum and alginate. Optimal conditions for xanthan gum
synthesis using different carbon sources, nitrogen sources were examined. Xanthan gum production is influenced by several factors
that include medium composition, cultivation conditions (temperature, pH, stirrer speed), fermentation time, and post-fermentation
conditions (heat treatment, recovery, purification). The present work revealed that the growth medium and organic solvents are the
main factors impacting the xanthan gum production. The properties that enable the application of xanthan gum in pharmaceutical
industries are emulsifying, thickening, stabilizing, film forming and gelling nature. Alginates are group of polysaccharides occurring
as structural components or as capsular materials in the cell wall of soil bacteria.
Azotobacter vinelandii
was used to produce alginate.
Exopolysaccharide production by
Azotobacter
in media supplemented with carbohydrates and some phenolic compounds was
investigated. Bacterial polysaccharides are produced on industrial scales and used as raw materials for food processing and medical
and industrial preparations. Alginate is a biomaterial that has found numerous applications in biomedical science and engineering
due to its favorable properties, including biocompatibility and ease of gelation.
Biography
Ilona Jonuškienė has completed her PhD from Kaunas University of Technology, Lithuania. She had training at Swedish University of Agricultural Sciences and
Copenhagen University. She is an Associate Professor and Chief of Bachelor and Master study programmes of Industrial Biotechnology at Kaunas University of
Technology, Faculty of Chemical technology. She has published more than 15 articles in reputed journals.
ilona.jonuskiene@ktu.ltIlona Jonuškienė, J Biotechnol Biomater 2017, 7:3(Suppl)
DOI: 10.4172/2155-952X-C1-077