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Volume 7, Issue 1 (Suppl) J Biotechnol Biomater
ISSN: 2155-952X JBTBM, an open access journal
March 20-21, 2017 Rome, Italy
&
15th World Congress on
2nd International Conference on
Biotechnology And Biotech Industries Meet
Enzymology and Molecular Biology
Enzymology & Mol. Biology 2017
Biotechnology Congress 2017
March 20-21, 2017
Kultanov B Zh et al., J Biotechnol Biomater 2017, 7:1(Suppl)
The state of oxidative stress in the body of women living in the Sub-Aral area
Kultanov B Zh, Ivasenko S A, Rakhimova B B and Kelmyalene A A
Karaganda State Medical University, Kazakhstan
The Aral crisis is recognized as one of the global environmental problems of our time. Existing environmental trouble in the region
is reflected on the health of the population in almost all areas of the Aral Sea region marked increase in the number of diseases
of the endocrine, nervous, digestive and urinary systems. Numerous studies conducted by scientists of Kazakhstan shows that the
health of population in recent decade’ s sub-Aral area continues to deteriorate. In the period of 2014-2016 years, the research team of
Karaganda State Medical University (KSMU) carried out the study of health status of population in Sub-Aral area in the medical and
biological direction under the state program. The study was conducted to determine the integrated approaches in solving problems of
the region, to carry out systematic monitoring of the health status of the population of Sub-Aral area and development of complex of
therapeutic and preventive measures based on the results obtained. This approach provides multidirectional nature of health research
not only in the zone of ecological adversity of Kyzylorda region, but also regions adjacent to Sub-Aral area, namely: Aktobe region
and South Kazakhstan regions. As a result of the research, we have established higher values of indicators of oxidative stress on the
markers of lipid peroxidation and DNA damage in the blood of women living in zone of ecological disaster in the Aralsk-city and
Aiteke-Bi-village (Kzylorda region) and women living in the area environmental pre-crisis state Kyrgyz-village (Aktobe region) and
Ulytau-village (Karaganda region), in the age group 30-39 years. The presence of elevated levels in blood markers of lipid peroxidation
and DNA damage indicates the development of a general oxidative stress in the body of women surveyed and indicates the presence
of most acute diseases, aggravation of chronic processes, intoxication and other pathological changes.
Biography
Kultanov B Zh has done his PhD from Kazakh Academy of Nutrition in Almaty in the year 2006. He is Head of the Department of Molecular Biology and Medical
Genetics of the Karaganda State Medical University. The main focus of his research is the study of the biochemical, morphological and molecular indicators of
reproductive status under the influence of physical and chemical factors. He is the author of various domestic and foreign editions of the textbooks of Biology
developed in the state language and Russian languages.