digestive-diseases-2016_scientifictracks-abstracts

Volume 6, Issue 8(Suppl)

J Gastrointest Dig Syst 2016

ISSN:2161-069X JGDS, an open access journal

Page 26

Notes:

Digestive Diseases 2016

December 08-09, 2016

conferenceseries

.com

Digestive Diseases

December 08-09, 2016 Dubai, UAE

International Conference on

A comparative study of Duplex Doppler ultrasound and blood indices as noninvasive predictors of

oesophageal varices in cirrhotic patients

Marwa El-Hossarya, Mona Shehataa, Lobna A Abo Alia

and

Khalid El-Shafeyb

Tanta University, Egypt

Background:

Endoscopic surveillance of oesophageal varices (OV) in cirrhotic patients is expensive and uncomfortable for the

patients. Therefore, there is a particular need for noninvasive predictors for OV.

Objective:

The aim of the present study was to evaluate the accuracy of ultrasound indices and blood indices as noninvasive OV

predictors among cirrhotic patients. Patients and methods A total of 61 cirrhotic patients were enrolled in this study and were

divided into two groups: 21 patients without OV and 40 patients with OV who were further subdivided into 24 patients with

small OV and 16 with large oesophageal varices (LOV). P2/MS, serum fibrosis markers (APRI, FIB4, Lok score, and Forns index),

abdominal ultrasonography [portal vein diameter (PVD), splenic index], platelet count/spleen diameter ratio (PC/SD), and Doppler

ultrasonography [portal vein velocity, splenoportal index, hepatic and splenic impedance indices, and hepatic venous waveform

(HVWF)] were assessed in all patients.

Results:

P2/MS was the best predictor of OV and LOV [area under the curve (AUC) 0.88 and 0.787, respectively] followed by PC/SD

(AUC 0.77 and 0.715, respectively). PVD, serum fibrosis markers, and serum albumin had the least accuracy for OV prediction. For

LOV predictions, Lok score had good accuracy (AUC 0.785) followed by serum albumin, PVD, APRI, and Forns index (AUC 0.72,

0.738, 0.734, and 0.738, respectively). Monophasic HVWF showed a good positive predictive value (85%) and specificity (80.95%) for

prediction of OV and good sensitivity (81.25%) and negative predictive value (81.25%) for LOV.

Conclusion:

P2/MS can identify OV and LOV in cirrhosis with high accuracy followed by PC/SD. Monophasic HVWF is a good

noninvasive predictor of OV and LOV in cirrhotic patients.

Biography

Marwa El-Hossarya is currently working in Department of Tropical Medicine, Tanta University, Tanta, Egypt

Marwa El-Hossarya et al., J Gastrointest Dig Syst 2016, 6:8(Suppl)