18 / 29
Page 54
Volume 9
Journal of Obesity & Weight Loss Therapy
ISSN: 2165-7904
JOINT EVENT
Childhood Obesity 2019
Diabetes Conference 2019
March 18-19, 2019
&
3
rd
World Congress on
Diabetes and Obesity
12
th
International Conferences on
Childhood Obesity and Nutrition
March 18-19, 2019 | Rome, Italy
Investigating the role of high pro-inflammatory diets (high fat diets) and childhood obesity in adult cancer
risk
A Knowell
and
S Brown
South Carolina State University, USA
C
hildhood obesity has been a growing epidemic in the United States with about one in three of children
considered overweight or obese. The increased number of overweight and obese children can be linked to
several factors including nutrition and social economic status. Obesity in children can lead to numerous health
complications including chronic inflammation and carcinogenesis. African American minorities are more likely to
be diagnosed and die from cancer than any other race. Therefore, this study aims to eliminate or reduce preventable
risk factors such as unhealthy nutrition and childhood obesity, which may reduce clinical manifestations of adult
cancer outcomes. Areas of South Carolina have a long history of being under-developed which contribute to
numerous problems such as obesity, poverty and sub-par health care. We have enrolled SC children from varying
degrees of rurality to determine if obesity and/or high-fat pro-inflammatory diets contribute to increased levels of
pro-inflammatory markers and obesity related genes to include: adiponectin, leptin, SAA1/2, Interleukin 1 and 6.
Subjects were randomized into obese and non-obese groups based on BMI guidelines and given a nutritional survey
to assess nutritional habits, exercise habits and body perceptions. The transcriptional levels of pro-inflammatory
genes were measured by quantitative Real-time polymerase chain reaction. The results suggest increased expression
of these pro-inflammatory markers is directly correlated to diet irrespective of weight class (normal, overweight,
obese). Reducing childhood obesity and pro-inflammatory diets are beneficial in the reduction of cancer risk and
will serve as preventive measures for early-stage onset of adult cancers.
J Obes Weight Loss Ther 2019, Volume 9
DOI: 10.4172/2165-7904-C1-091