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conferenceseries
.com
Volume 2, Issue 4 (Suppl)
Breast Can Curr Res, an open access journal
Breast Pathology 2017
August 23-24, 2017
August 23-24, 2017 Toronto, Canada
4
th
World Congress on
Breast Pathology and Cancer Diagnosis
Potentials of lung injury after single electron beam postmastectomy radiotherapy
Hiba Omer
Imam Abdul Rahman Bin Faisal University, Saudi Arabia
B
reast cancer patients are treated by a variety of options. Electron beams are utilized in the irradiation of the chest wall
post mastectomy due to its dose distribution in the irradiated body, which does not penetrate deep into the body. Our
objectives were to determine the possibility of inducing lung injuries during postmastectomy radiotherapy (PMRT) using
single-field electron beams. Electron beams with different energies, and gantry angles were simulated using EGSnrc and
checked for consistency with the measured beams. The simulated beams were then used for irradiating the chest wall in
PMRT. XSTING software tool was used to superimpose the beam distribution on the CT data and generate dose volume
histograms. The normal-tissue-complications-probability of the lung was evaluated. The dose response of the lung and
potentials for developing lung fibrosis and pneumonitis were evaluated using DORES, a home built tool at the medical
physics department in the University Hospital in Larisa NTCP increases with energy and with gantry angle. Below 15 MeV
(which had given very high and unacceptable NTCP values) the largest value of NTCP of fibrosis was 0.036, for 12 MeV,
gantry angle 60. The largest value of NTCP of radiation induced pneumonitis was 0.044, for 12 MeV, gantry angle 60. These
values indicate low potentials of lung induced injuries, but were at the expense of appropriate target coverage
Biography
Hiba Omer has done her PhD in medical Physics from University of Thessaly, Greece. She is an Assistant Professor of Medical University of Dammam, KSA
and Member of several scientific and women societies. Her research areas are Education, Medical Physics, radiobiology, simulation; public education. She
has done several research publications as well.
hibaha@yahoo.comHiba Omer, Breast Can Curr Res 2017, 2:4 (Suppl)
DOI: 10.4172/2572-4118-C1-008