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Volume 8, Issue 6 (Suppl)
J Bioremediat Biodegrad, an open access journal
ISSN:2155-6199
Biopolymers & Bioplastics 2017
October 19-20, 2017
October 19-20, 2017 San Francisco, USA
7
th
International Conference and Exhibition on
Biopolymers and Bioplastics
Alginate/κ-Carrageenan and alginate/gelatin composite hydrogel beads for controlled drug release of
curcumin
Jinu George
Sacred Heart College Thevara, India
H
ydogel beads based on natural polymers like alginate, κ-carrageenan and gelatin represent an efficient scaffold for targeted
hydrophobic drug delivery. We report herein the development and characterization different formulations of hydrogel systems
based on the above mentioned polymers having adequate properties as drug delivery matrices. Different combinations of alginate/κ-
carrageenan and alginate/gelatin hydrogel beads were developed and drug release properties were compared using curcumin as a
model drug. Morphology, swelling behavior and analytical characterization of the matrices were carried out using IR spectroscopy
and SEM. Alginate/κ-carrageenan hydrogel beads with 50:50 weight ratio exhibited higher swelling and better drug release percentage
than compared to other beads. Encapsulation efficiency and drug release behavior of different formulations of alginate/κ-carrageenan
and alginate/gelatin, indicates that the polymer blends synthesized possess considerable potential in pharmaceutical and medicinal
applications.
jinujacob@shcollege.ac.inJ Bioremediat Biodegrad 2017, 8:6 (Suppl)
DOI: 10.4172/2155-6199-C1-012