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Volume 8, Issue 6 (Suppl)

J Bioremediat Biodegrad, an open access journal

ISSN:2155-6199

Biopolymers & Bioplastics 2017

October 19-20, 2017

October 19-20, 2017 San Francisco, USA

7

th

International Conference and Exhibition on

Biopolymers and Bioplastics

Biopolymeric nanoparticles in analytical sensing tools

Meenakshi Singh

and

Juhi Srivastava

Banaras Hindu University, India

B

iopolymer derivatized nanoparticles offer many advantages to be incorporated in various tools and technologies being developed

by sensing fraternity. Chitosan, starch and many other biopolymers are suitable biopolymers as these natural polymers have

excellent properties such as biocompatibility, biodegradability, non-toxicity and adsorption properties. Being environment friendly

with such excellent characteristics prompted us to exploit it as polymeric format for developing molecularly imprinted polymers

(MIP). Molecular imprinting offers creation of artificial receptor in a facile manner. MIPs often named as ‘artificial enzymes’ and/

or ‘artificial antibodies’ are one of the most promising technique in sensor designing. The major benefits of MIPs compared with

antibodies are their high and almost unlimited-stability and easy way of preparation at a large scale that unquestionably outperform

antibodies in terms of costs. Nanoparticles of chitosan and starch with selective molecular recognition properties are attractive as

they can easily be incorporated into existing analytical or preparative platforms to unravel various practical problems. An attempt is

made in our laboratory to use biopolymer chitosan and starch as polymeric formats to imprint some analytes in nano-configuration.

Chitosan, bearing primary amine groups, soluble in aqueous medium at acidic pH < 6.0, endowing them positive charge (-NH

3

+

), can

easily be attached with negatively charged surface or can adsorb negatively charged material, hence, commonly used for dispersing

nanomaterials and immobilizing the target material for preparing sensing matrices. A simple, facile, cost-effective, sensitive and

selective but still easy to fabricate sensors by molecular imprinting of biopolymer chitosan/starch in nanoformat are effective eco-

friendly alternatives to other synthetic sensing matrices and they were able to detect analytes at trace level. Being simple, inexpensive,

ecofriendly, rapid, high sensitivity and improved detection limit are promising for these tools.

meenakshi_s4@rediffmail.com

J Bioremediat Biodegrad 2017, 8:6 (Suppl)

DOI: 10.4172/2155-6199-C1-012