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Volume 8, Issue 6 (Suppl)
J Bioremediat Biodegrad, an open access journal
ISSN:2155-6199
Biopolymers & Bioplastics 2017
October 19-20, 2017
October 19-20, 2017 San Francisco, USA
7
th
International Conference and Exhibition on
Biopolymers and Bioplastics
The effect of cross-linking and anti-microbial agent on the performance of poly(vinyl alcohol) and cellulose
acetate based membranes designed for wound dressings
Tushar Bambharoliya
1
, Radhika Vaid
1
, Aneela Sabir
2
, Atif Islam
2
, Tahir Jamil
2
and Martin W. King
1
North Carolina State University, USA
2
University of the Punjab, Pakistan
3
Donghua University, China
I
n recent years, research focusing on developing biomedical products from various polymeric membranes has witnessed a
tremendous expansion attributed to their unique properties. Flexible thin polymeric membranes prepared from bioresorbable and
biocompatible polymers, having a cross-linked network, are known to absorb and maintain their physical structure and integrity
at the site of implantation. This generates the release of various biologically active components thus helping to restore the structure
of injured and diseased tissues. The present work focuses on evaluating polyvinyl alcohol (PVA) and cellulose acetate (CA) based
membranes cross-linked with tetraethylorthosilicate (TEOS) for wound dressing applications. These membranes contain varying
percentages of alumina (Al
2
O
3
) and chitosan to provide them with antimicrobial properties. Previously, these membranes were
developed for filtration and desalination, and we plan to use them as occlusive wound dressings, where the exudate absorption,
water vapor transmission and ion exchange will be crucial performance properties. Following synthesis, this project is currently in
its characterization phase, which is critical to wound dressings development. The thermal, chemical and surface characterization of
the PVA and CA based membranes is being executed using TGA, FTIR, SEM, optical microscopy, TOF-SIMS and XPS. The samples
were observed to have cross-links by identifying the presence of certain peaks throughout the FTIR fingerprint region. Additionally,
through SEM we could witness a smooth continuous surface and layered cross-section lacking porosity both on the surface and
through the cross-section for the samples. Further, TGA data confirmed that the elevated temperature for processing and sterilization
will not contribute to premature degradation since the degradation peak was above 250°C for all samples. Characterization of these
membranes to analyze their surface and antimicrobial properties is still ongoing.
tbambha@ncsu.eduJ Bioremediat Biodegrad 2017, 8:6 (Suppl)
DOI: 10.4172/2155-6199-C1-012