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.com
Volume 8
Journal of Biotechnology and Biomaterials
ISSN: 2155-952X
Biomaterials 2018
March 05-06, 2018
March 05-06, 2018 | Berlin, Germany
3
rd
Annual Conference and Expo on
Biomaterials
In vitro
bioactivity of a biocomposite HA/ZrO
2
fabricated from bovine bone by high energy ball
milling technique
Fatemeh Mohammaddoost
1
and
Joanna Borowiec
2
1
UPM, Malaysia
2
Sichuan University, China
T
he superior biocompatibility and bioactivity of hydroxyapatite (HA) ceramic has attracted much attention as a substitute
material in bone grafting. In the present work, the HA was produce from bovine bone while zirconia powder was supplied
by the China (Mainland) trading company. In this work, HA/ZrO
2
biocomposite prepared with different wt % (0.0, 0.2, 0.4 and
0.8) of ZrO
2
concentrate, sintered at 1250 °C, 1 h milling time. In this project, the bioactivity test was carried out by soaking the
sample in simulated body fluid SBF solution, 7 and 15 days in an incubator maintained at 36.5
o
C. For instance, bioactivity was
studied by soaking the samples in the SBF solution followed by the SEM, EDX analysis as well as XRD. The SEM results showed
the apatite on the surface of HA/ZrO
2
biocomposite on a 7 days growth and when the immersion time increased to 15 days, the
growth of apatite on the surface increased more. Other than that, the EDX showed that the covered layer on the surface was P
and Ca as well as O. The XRD results showed that the soaked HA/ZrO
2
biocomposite composed HA, α-TCP, β-TCP and ZrO
2
and no other phases were detected.
Recent Publications
1. Barakat N A, Khil M S, Omran A, Sheikh F A and Kim H Y (2009) Extraction of pure natural hydroxyapatite from
the bovine bones bio waste by three different methods. Journal of Materials Processing Technology 209(7):3408-15.
2. Chavan P N, Bahir MM, Mene R U,Mahabole M P and Khairnar R S (2010) Study of nanobiomaterial hydroxyapatite
in simulated body fluid: Formation and growth of apatite. Materials Science and Engineering:B 168(1):224-230.
3. Radha G, Balakumar S, Venkatesan B and Vellaichamy E (2015) Evaluation of hemocompatibility and
in vitro
immersion on microwave-assisted hydroxyapatite-alumina nanobiocomposite. Materials Science and Engineering C:
Materials for Biological Applications 50:143-150.
4. Ruksudjarit A, Pengpat K, Rujijanagul G and Tunkasiri T(2008) Synthesis and characterization of nanocrystalline
hydroxyapatite from natural bovine bone. Current Applied Physics 8(3):270-272.
5. Mittal M, Nath S and Prakash,S (2013) Improvement in mechanical properties of plasma sprayed hydroxyapatite
coatings by Al2O3 reinforcement. Materials Science and Engineering: C 33(5):2838-2845.
Biography
Fatemeh Mohammaddoost has obtained her Master’s degree in Material Science and Engineering from University Putra Malaysia. She has her expertise in
biomaterial, synthesis from bio waste to use as a medical replacement. Her studies based on high energy ball milling technique to improve the physical properties
which is a new method to synthesis hydroxyapatite from bio waste, to create new pathways for improving medical application by simulation body fluid test.
oliamoh.moh@gmail.comFatemeh Mohammaddoost et al., J Biotechnol Biomater 2018, Volume 8
DOI: 10.4172/2155-952X-C1-089