38 / 38
Page 66
conferenceseries
.com
Volume 07
Advances in Crop Science and Technology
ISSN: 2329-8863
Agri 2019
August 15-16, 2019
August 15-16, 2019 | Rome, Italy
14
th
International Conference on
Agriculture & Horticulture
Radical scavenging activity of flavonoids increased by metal ions
Rui-Min Han, Yi Xu, Ling-Ling Qian
and
Jian-Ping Zhang,
Renmin University of China, China
F
lavonoids are secondary plant metabolities of the polyphenol family with a diversity of biological functions.
Most metal-flavonoid complexes are found to have considerably higher antioxidant effects than free flavonoids.
Molecular mechanisms of antioxidant activity of flavonoids increased by metal ions are poorly understood.
In our studies, binding of flavonoids (apigenin, kaempferol and luteolin) with metal ions, and radical scavenging
activities of corresponding complexes were investigated in detail. Structural factors, such as coordinate proportions
of metal ions and flavonoids and steric orientations affecting activities of metal-flavonoid complexes as antioxidants,
are elucidated.
Recent Publications
1. Xu Y, Qian L-L, Yang J, Han R-M, Zhang J-P, Skibsted L H (2018) Kaempferol Binding to Zinc(II), E cient
Radical Scavenging through Increased Phenol Acidity. J. Phys. Chem. B 122: 10108−10117.
2. Liu X-C, Du H-H, Fu L-M, Han R-M, Wang P, Ai X-C, Zhang J-P, Skibsted L H (2018) Integrity of Membrane
Structures in Giant Unilamellar Vesicles as Assay for Antioxidants and Prooxidants. Anal. Chem. 90: 2126−2133.
3. Yang J, Xu Y, Liu H-Y, Han R-M, Zhang J-P, Skibsted L H (2017) Genistein Binding to Copper(II)-Solvent
Dependence and Effects on Radical Scavenging. Molecules 22: 1757−1771.
4. Pereira J C M, Iretskii A V, Han R-M, Peter C. Ford (2015) Dinitrosyl Iron Complexes with Cysteine. Kinetics
Studies of the Formation and Reactions of DNICs in Aqueous Solution. J. Am. Chem. Soc. 137: 328−336.
5. Han R-M, Cheng H, Feng R, Li D-D, Lai W, Zhang J-P, Skibsted LH (2014) β‑Carotene As a Lipophilic Scavenger
of Nitric Oxide. J. Phys. Chem. B 118: 11659−11666.
Biography
Rui-Min Han, Associate professor in Department of Chemistry, Renmin University of China, Beijing, 100872 Research interest: Antioxidant mechanism and
application of phytochemicals and their metal complexes. Speciality: time-resolved dynamics (stopped-flow, laser photolysis).
rmhan@ruc.edu.cnRui-Min Han et al., Adv Crop Sci Tech 2019, Volume 07
Figure 1. Absorbances for (a) DPPH• at 516 nm, and (b)
β-Car•+ at 940 nm scavenged and β-carotene ground
state bleaching at 510 nm recovered by indicated ratio
of kaempferol (Kaem) and Zn(II). The concentration of
Kaem is 100 μM.