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Volume 8
Journal of Biotechnology & Biomaterials
ISSN: 2155-952X
Adv.Biotech 2018
November 15-17, 2018
November 15-17, 2018 | Berlin, Germany
4
th
International Conference on
Advances in Biotechnology and Bioscience
Hybrid nanostructures of inorganic particles and biomolecules: Fabrication, antimicrobial activity
and application in deep-UV imaging of live cells
Vladimir Djoković
University of Belgrade, Serbia
H
ybrid nanostructures that comprise inorganic nanoparticles (noble metals, semiconductors) and biomolecules received
a considerable attention in last decades due to a number of interesting fundamental properties as well as a wide range
of possible applications. Here, we present the results on two types of hybrid structures: noble metal (Ag, Au) nanoparticles
functionalized with small biological molecules (tryptophan, riboflavin) and ZnO biomacromolecule (cellulose, alginate)
hybrids. The obtained materials were studied in detail by microscopic (TEM, SEM) and optical (PL and UV vis) techniques.
The antimicrobial activity of the ZnO-, Ag- and ZnO/Ag-biomolecule hybrids was tested against the
Staphylococcus aureus,
Escherichia coli
and
Candida albicans
pathogens. Silver nanoparticles functionalized with amino acid tryptophan and gold
nanoparticles bi-functionalized with tryptophan and riboflavin were tested as fluorescent probes for deep-UV (DUV) imaging
of microbial and cancer cells. DUV imaging was performed on DISCO beam line of synchrotron SOEIL, France. ZnO-
biomacromolecule hybrids exhibit other interesting properties such as ability to immobilize antibodies, catalytic activity and a
strong CO
2
absorption, which will also be presented.
Biography
Vladimir Djoković has completed his PhD in Physics at University of Belgrade, Faculty of Physics in 1999. He spent two year as a Postdoctoral fellow at University
of the Free State, South Africa. In last couple of years, he was a Visiting Professor/Researcher at NASA-University Research Center, North Carolina Central
University. He has published two book chapters and more than 60 papers in ISI journals. He is a leader of polymer nanocomposite group at Vinča Institute from
2005 and a Professor of Polymer Physics at Faculty of Physics, University of Belgrade.
djokovic@vinca.rsVladimir Djoković, J Biotechnol Biomater 2018, Volume 8
DOI: 10.4172/2155-952X-C6-103