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Volume 4, Issue 3 (Suppl) Adv Crop Sci Tech
ISSN: 2329-8863 ACST, an open access journal
Page 76
Notes:
Plant Genomics 2016
July 14-15, 2016
conferenceseries.com
July 14-15, 2016 Brisbane, Australia
4th International Conference on Plant Genomics
Understanding redox sensing and signaling through the identification and functional characterization
of redox-sensitive proteins
Yiji Xia, Yimin Li, Pei Liu, Huan Zhong, Shuying Pang and Hailei Zhang
Hong Kong Baptist University, Hong Kong
Acommon physiological response to various environmental stresses in plants is accumulation of reactive oxygen species (ROS).
ROS can cause oxidative damage to macro biomolecules. On the other hand, ROS have increasingly been recognized as important
regulators in physiological and developmental pathways. ROS signaling is mediated largely through actions on redox-sensitive
proteins that undergo oxidative modifications in response to perturbation of cellular redox states. We have developed gel-based
and gel-free (OxiTRAQ) quantitative redox proteomics methods to identify Arabidopsis proteins whose thiols underwent oxidative
modifications in response to treatments of ROS and the defense elicitors (salicylate and flagellin). The redox-sensitive proteins are
involved in a variety of biological processes including chromatin remodeling and transcription, mRNA processing, post-translational
modifications and primary and secondary metabolism. A redox-sensitive bZIP transcription factor in Arabidopsis has been found to
act as a redox sensor and mediate expression of oxidative stress responsive genes through its oxidation/reduction. Our progresses in
developing redox proteomics methods and in characterizing the role of the transcription factor in redox sensing and stress responses
will be presented.
Biography
Yiji Xia is currently a Professor and Head of Department of Biology at Hong Kong Baptist University. He has received his PhD in Genetics from Iowa State University
in 1997 and was a Joint Postdoctoral Associate at Salk Institute/Noble Foundation from 1997 to 1999. After working at Akkadix Corporation (San Diego, USA) as
a Senior Scientist from 2000 to 2001, he has joined Danforth Plant Science Center (St. Louis, USA) as Principal Investigator. Since 2009, he has been working
at HKBU. He has published over 40 research articles in Nature, EMBO Journal, EMBO Reports, Plant Cell, PNAS and other journals with a total citation count of
over 4,900. His main research focus is on plant stress responses, particularly on redox sensing and epigenetic and transcriptional regulation in response to biotic
and abiotic stress.
Yiji Xia et al., Adv Crop Sci Tech 2016, 4:3 (Suppl)