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Volume 04 Journal of Clinical Infectious Diseases & Practice
ISSN: 2476-213X Rare Diseases Congress 2019
June 17-18, 2019
June 17-18, 2019 | Berlin, Germany
9th World Congress on
Rare Diseases and Orphan Drugs
Rare oral soft tissue metastasis: An overview
Cinzia Casu and Maria Giulia Nosotti
President of AIRO RDH, Italy
Metastasis to the oral cavity is a rare event and constitutes 1% of all oral cavity malignancies. We would like
to report the cases in the literature of rare oral soft tissue metastasis. We reported oral metastasis on the
cheeks, on the lips, on the floor of the mouth, on soft palate and on the uvula. We had found only eight cases of oral
metastasis on the lips searching on PubMed with the keywords “oral metastasis in lips”, “lip metastasis”. The primary
malignant tumor that most frequently undergo metastasis at the labial level is certainly the renal tumor with five
cases out of eight. In five cases the upper lip was affected, there was one case in which metastasis was present in both
lips, and this is a very interesting data because the other malignant diseases are more frequent in the lower lip. We
had found in Pubmed literature only seven cases of oral metastasis on the floor of the mouth with the keywords “oral
metastasis in the floor of the mouth”, “floor of the mouth metastasis”; we found only five cases of oral metastasis on
the cheek with keywords “oral metastasis on the cheek”. Oral lesion of 54 mm of maximum diameter was reported.
We have searched cases of metastasis on the soft palate and on the uvula, with the key words “ oral metastasis on
soft palate” and “oral metastasis on uvula” and we have found respectively three and one (from the kidney) results.
The malignant tumors that undergo metastasis at the soft palate were renal, bronchial and lung carcinomas. This
overview underlines how this oral disease can sometimes be misunderstood, and the importance of regular checks
in patients who already have a diagnosis of malignancy.
Recent Publications
1. Irani S (2016) Metastasis to the oral soft tissues: A review of 412 cases. J Int Soc Prev Community Dent. 6(5):393-401.
2. Irani S (2016) Pre-cancerous lesions in the oral and maxillofacial region: a literature review with special focus on
etiopathogenesis. Iran J Pathol. 11(4):303-322.
3. Jatti D, Puri G, Aravinda K and Dheer D S (2015) An atypical metastasis of renal clear cell carcinoma to the upper lip:
a case report. J Oral Maxillofac Surg. 73(2):371.e1-6.
4. Mintz S M and Radecki C (1988) Metastatic bronchial carcinoid tumor of the soft palate: report of a case. J Oral
Maxillofac Surg. 46(6):516-8.
5. Lansigan N C Jr, Benisch B M and Sidoti J (1973) Renal carcinoma presenting as metastasis to uvula. Urology.
2(4):449-51.
Biography
Cinzia Casu has completed her Graduation in 2010. Currently, she is working at her Private Dental Practice in Cagliari, Italy. She had concluded a bienal
Master’s degree on Oral Surgery and Pathology at the University of Parma in 2015, and others courses of oral pathology. She is the author of several national
and international articles and a monograph. She is the President of AIRO (Italian Academy of Oral Research). She is an Editorial Member of some international
journals such as Biology and Medicine Case Reports and Current Analysis on Dentistry. She was a Speaker in Italian, European, and World congresses.
Cinzia Casu et al., J Clin Infect Dis Pract 2019, Volume 04