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Volume 6, Issue 5 (Suppl)
OMICS J Radiol, an open access journal
ISSN: 2167-7964
Radiology and Oncology 2017
October 19-20, 2017
World Congress on
October 19-20, 2017 | New York, USA
Radiology and Oncology
Medication related osteonecrosis of the jaw (MRONJ): Computer assisted assessment of pathological
skeletal changes
Britt-Isabelle Berg
1
, Kjeller G
2
and
Kober C
3
1
University Hospital of Basel, Switzerland
2
The Sahlgrenska Academy, Sweden
3
HAW Hamburg, Germany
M
edication related pathological changes in mandibular bone due to oncologic treatment are a serious burden. Clear display of
the progression of the disease is still a challenge in clinical diagnosis. Therefore, a detailed research project focused on CT-/
CBCT-based visualization of necrotic changes was initiated. To start with, all available CT-/CBCT data of the patient are registered
on a suitable reference. After several refined image processing and programming steps, the data are subjected to slice oriented direct
volume rendering with various (mostly logarithmic) transfer functions specially designed for the respective purpose. For medication
related pathological changes, besides destructive skeletal changes, severe sclerosing processes within trabecular structure are reported.
Destructive processes correspond to decreased Hounsfield values, whereas sclerosation is indicated by increasing ones. For this
purpose, we refer to visualization based on an “inverted temperature color scale”. As kind of control, visualization based on healthy
subjects can be considered. Additionally, we compare the affected and the non-affected (or less affected) mandibular side. For healthy
controls, the new method provides a clear and uniform appearance of the alveolar ridge. However, for pathological cases, serious
changes in trabecular bone are ipsilaterally reported. Considering several follow-up CT data, progression of the described changes
over the whole mandible was observed. Recent achievements for computer assisted visualization for necrotic changes in mandibular
bone are presented. Besides diagnostic significance, this research is aimed at diagnosis efficiency. The new visualization methods help
the surgeon to examine the pathological changes at one glance.
Biography
Britt-Isabelle Berg has compelted her Medical degree at the University of Lübeck and her Dental degree at the Universiy of Freiburg, Germany. Since 2005, she works at the
Clinic of Cranio- Maxillofacial Surgery at the University Hospital Basel, Switzerland. Currently, she is in charge of the Dentomaxillofacial Radiology at the Universiy Hospital
Basel. In between, she worked in Great Britain (Eastbourne, Brighton), France (Paris) and the United States (New York City). She has authored/co-authored over 20 papers.
She has presented over 30 lectures herself and was co-author in over 50 other presentations (national and international).
isabelle.berg@usb.chBritt-Isabelle Berg et al., OMICS J Radiol 2017, 6:5 (Suppl)
DOI: 10.4172/2167-7964-C1-015