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Volume 6, Issue 5 (Suppl)
OMICS J Radiol, an open access journal
ISSN: 2167-7964
Radiology and Oncology 2017
October 19-20, 2017
World Congress on
October 19-20, 2017 | New York, USA
Radiology and Oncology
Meta-analysis and specificity comparison between 13C-FDG PET and 13C-hyperpolarized MR
spectroscopic imaging in cancer today
Janet Cordero
and
Subhendra Sarkar
New York City College of Technoogy, USA
T
he ability of PET and MRI to image cancers has been a very important aspect of clinical management. The ability to detect cancer
by using different radiologic modalities with appropriate fusion imaging can help visualize cancer at various stages with various
sensitivity and specificity. However, the two most promising modality for high sensitivity and specificity are 13C FDG-PET and
13-C Hyperpolarized MR Spectroscopic imaging (we will call Hyper MRSI) and may reduce or eliminate the need for biopsy. We
have analyzed radiology and oncology literature for past ten years to compare the specificity of these two techniques. In our meta-
analysis, Hyper MRSI plays a unique role for prostate as well as for a few types of brain cancer including glioma that is more useful
for staging than 13-C PET. On the other hand, PET may be able to treat while detect cancer using ImmunoPET functionality. Since
the background metabolic activity, e.g. in glioma, competes with tumor bed in Hyper MRSI, its effectiveness (signal/noise and thus
sensitivity) may change with tumor grade and individual patient’s brain metabolism. Resting brain state MRSI may require special
patient preparation to reduce such background metabolism and high field MR systems could perform better. Outside brain, Hyper
MRSI may be superior than FDG-PET. Specific advantages and disadvantages of both modalities will be discussed.
Biography
Janet Cordero is a BS student in Radiologic Science at New York City College of Technology. She holds an AAS in Nuclear Medicine Technology from Bronx Community
College, New York. She is a licensed Nuclear Medicine and CT Technologist and has presented her work in lung cancer in Annual College conference in New York, in
2016. She has been working in Cancer Imaging for a year in Undergraduate research. She also holds a Technologist job at Winthrop Universsity hospital in Mineola, NY.
corderojanet@yahoo.comJanet Cordero et al., OMICS J Radiol 2017, 6:5 (Suppl)
DOI: 10.4172/2167-7964-C1-015