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Volume 6, Issue 5 (Suppl)
OMICS J Radiol, an open access journal
ISSN: 2167-7964
Radiology and Oncology 2017
October 19-20, 2017
World Congress on
October 19-20, 2017 | New York, USA
Radiology and Oncology
Liquid crystal contact thermography in breast cancer detection
Pawel Basta
1
, Jan Skupien
1
, Tadeusz J Popiela
1
, Agnieszka Byszek
4
, Anna Cwierz
2,4
, Diana Hodorowicz-Zaniewska
1
, Piotr Kasprzak
3
, Agnieszka Kotlarz
1
,
Wojciech Rudnicki
2,4
and
Marcin Trzyna
4
1
Jagiellonian University, Poland
2
Oncological Centre-Cracow Branch, Poland
3
Lower Silesian Oncology Center, Poland
4
Braster S A Company, Poland
Introduction:
The most efficient way to decrease breast cancer-related mortality is its early detection. Thermography is an imaging
method postulated to detect neoplasms through tumor cell’s increased metabolism in comparison to healthy cells. Despite some
promising results, thermography has not been, so far, accepted as valuable breast lesions detection method, mainly due to a lack
of standardized protocols and conditions of performing the examination and poor quality of many research articles undermining
credibility of obtained results. A device called Braster Tester has been developed to provide high-quality contact thermography images
of the breast. A controlled, prospective observational study has been designed to determine the credibility of the new technology.
Aim:
The aim of this study was an evaluation of the diagnostic accuracy in detection of breast pathology with the technology of the
liquid crystal contact thermography.
Method:
A liquid crystal contact thermography was performed by 274 women referred to breast pathology outpatient units for
verification of abnormal, either breast ultrasound or mammography examination. The final analysis included 95 women aged 25–49
years with BIRADS-US 4 or 5 category in breast ultrasound scan (ArmA), 73 women aged ≥25 years with BIRADS-US 1 or 2 category
in breast ultrasound scan (Arm B), and 87 women aged ≥50 years with BIRADS-US 4 or 5 category in breast ultrasound scan (Arm
C). The parameters for assessing the effectiveness of the liquid crystal contact thermography: C-statistic, sensitivity, specificity and
diagnostic accuracy defined as the proportion of true positives and true negatives. Among all thermographic, results were calculated
using exact McNemar’s test and Wald’s test in respect to final pathology reports of the breast specimens.
Results:
The diagnostic efficacy of the liquid crystal contact thermography defined as above demonstrated a sensitivity of 81.5% (95%
CI: 64.1; 92.6) and specificity of 87% (95% CI: 79.7; 92.4) in women <50 years of age and sensitivity of 77.8% (95% CI: 67.2; 86.2) and
specificity of 62.5% (95% CI: 48.5; 75.1) in women ≥50 years of age. In the group of women without breast pathology (BIRADS 1 and
2), the rate of false-positive thermography was similar to that observed in women with abnormal breast ultrasound without breast
cancer (22.5% and 37.5% in women <50 and ≥50 years of age, respectively).
Conclusions:
The results of this study illustrate promising trends and an accepted efficacy of liquid crystal contact thermography
in highlighting women with a higher risk of breast pathology, especially breast cancer. This statement is more evident especially in
woman <50, thus the technology may have a chance to support other modalities in that goup of women in breast cancer prevention.
Biography
Dr Paweł Basta is an experienced gynecologist-obstetrician. He graduated from the Faculty of Medicine, Collegium Medicum in Cracow. In 2007 he completed his spe-
cialization in obstetrics and gynecology at the Jagiellonian University in Cracow and in 2013 he completed specialization in oncology gynecology also at the Jagiellonian
University in Cracow, however as a part of his studies he worked as an assistant at a prestigious University College London Hospital in the United Kingdom. He is a recog-
nized doctor specialized in the early detection of breast cancer and in the malignant neoplasia of the female reproductive system. He enjoys the respect and trust of patients
who underline his commitment to his work and his willingness to help, as well as the individual approach to each patient and his or her problem. Dr Paweł Basta is also an
academic teacher of the Medical Faculty and Medical School for Foreign Students of the Jagiellonian University Medical College. Moreover, Paweł Basta is an author and
co-author of numerous medical publications. He was also a speaker at many medical conventions, conferences and meetings taking place both in Europe and the U.S.
a.byszek@braster.euPawel Basta et al., OMICS J Radiol 2017, 6:5 (Suppl)
DOI: 10.4172/2167-7964-C1-015