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Volume 5 Issue 4(Suppl) Clin Pharmacol Biopharm
ISSN: 2167-065X CPB, an open access journal
Page 20
Pharma & Clinical Pharmacy Congress 2016
November 07-09, 2016
conferenceseries.com
November 07-09, 2016 Las Vegas, Nevada, USA
4th International
Pharma & Clinical Pharmacy Congress
Roseane Maria Maia Santos, Clin Pharmacol Biopharm 2016, 5:4(Suppl)
The Search for genomic markers for coffee consumption
The turnaround of the millennium brought us lots of expectation in terms of world market globalization economy, planet
environment preservation and energy resources to mention a few. However, one of the most important discoveries in
the science eld was the unveiling of the human genome. Since then, most of the attention has turned to understanding
the function of many genes and genomic fragments and their relationship with human pathophysiology. Much has been
accomplished so far, such as BRCA1 and BRCA2 markers for breast cancer; HOXB13 gene for prostate cancer; APOE ε4 for
Alzheimer’s disease and many others that lead to the possibility of genetic testing to predict the risk of developing the disease,
if the mutant variant gene is expressed in the individual genome.
Co ee is the mostly widely consumed beverage worldwide with known health bene ts. e genomic approach to search
for speci c regions in the human DNA that are highly expressed within the co ee consumers is also a recent phenomenon.
Genome-wide association studies (GWAS) have identi ed a number of regions of interest associated with co ee consumption.
A consortium actually was created with the participation of researchers from all over the world, in an e ort to accelerate these
ndings. e purpose is to understand the relationship between parts of the human DNA and the increased or decreased co ee
use and its correlation with the prevention of a series of diseases as type-2 diabetes, cancers and neurodegenerative diseases
that account for the majority of the chronic disorders that a ict our post-millennium population.
Biography
Santos has completed his PhD from SUNY at Buffalo and is an Associate Professor at Department of Pharmaceutical Sciences at School of Pharmacy. She has
a company devoted to research and consultancy, Dr. Coffee in Savannah as well as a laboratory devoted to research on Coffee and health benefits. She has
published many papers, participated as peer reviewer for various journals and has written chapters and textbooks in Portuguese, English and Korean.
Roseane Maria Maia Santos
South University School of Pharmacy, USA