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Volume 8
Journal of Gastrointestinal & Digestive System
ISSN: 2161-069X
Page 58
JOINT EVENT
Pediatric Gastro 2018
Digestive Diseases 2018
October 22-23, 2018
October 22-23, 2018 Berlin, Germany
3
rd
International Conference on
Digestive and Metabolic Diseases
Pediatric Gastroenterology Hepatology & Nutrition
13
th
International Conference on
&
The prognostic value of 24-hour urine sodium (24-hr una) in cirrhotic patients with ascites on diuretics
Sukanta Chandra Das
General Hospital, Narayanganj, Bangladesh
Background:
Ascites due to cirrhosis can be mobilized with sodium restriction (88 mEq/day) and diuretics.Patients with
non-responder to diuretics may have pre-hepatorenal syndrome and a poor prognosis.Diuretic response can be monitored by
measuring 24-hr UNa which can also be a prognostic marker.The aim of this study was to evaluate the value of 24-hr UNa as
a prognostic marker in cirrhotic patient with ascites on diuretics.
Methods:
This cross-sectional study included 100 patients of cirrhosis on diuretics.24-hour urine was collected properly and
tested
accordingly.Atthe same time liver and renal function tests were done to calculate MELD and CTP score.
Results:
Out of 100, 48 (48%) subjects had excreted ≥78 mmol/d of sodium and 52 (52%) subjects excreted <78mmol/d.64
subjects belong to CTPS “B” and 36 in CTPS “C”group.Majority of the cases (81.3%)of CTPS “B” group had excreted ≥78 mmol
sodium/day and 51.9% patients of the CTPS “C” group had 24hr urinary sodium <78 mmol
/day.Inpatients who excreted <
78 mmol/day MELD score was 17.71 ± 4.51 and it was 14.60 ± 2.98 in patients who excreted ≥78mmol/day of urinary sodium.
These differences were statistically significant (p<0.001).
Conclusion:
This study showed that advanced cirrhosis have relatively lower natriuresis in response to
diuretics.So, 24-hr UNa
can be considered as a prognostic indicator.But multicentered studies are needed for further recommendation.
drsukantadmc@gmail.comJ Gastrointest Dig Syst 2018, Volume 8
DOI: 10.4172/2161-069X-C7-083