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Volume 8
Journal of Clinical & Experimental Pathology
Pathology Summit 2018
July 02-03, 2018
July 02-03, 2018 Bangkok, Thailand
15
th
Global Experts Meeting on
Pathology and Laboratory Medicine
Granular cell tumor clinical spectrum of the benign and malignant entity
Fariha Kauser
1
, Anshoo Agarwal
2
and Arvind Sinha
2
1
Civil Hospital Karachi, Pakistan
2
B.P. Koirala Institute of Health Sciences, Nepal
G
ranular cell tumors are uncommon lesions, although the head and neck region accounts for approximately 50% of all
lesions. The basic cell of origin is now thought to be neural, although past studies indicated an origin from striated
muscle or an origin from histiocytes, fibroblasts or pericytes. The tumor generally occurs in middle or older aged adults.
Lesions often demonstrate pallor or a yellowish discoloration and typically have a smooth surface. As most of the granular
cell tumors are benign, surgical excision of the lesion is the treatment of choice. We report four cases of granular cell tumors:
Case-1: Mimicking as metastatic skin nodule in umbilical region diagnosed at B.P. Koirala Institute of Health Sciences, Case-
2: Occurring in a 3 year old child, Case-3: Granular cell tumor co-existing with squamous cell carcinoma in respiratory tract
and Case-4: Granular cell myoblastoma occurring in a burn case, studied at Civil Hospital Karachi. The histopathologic
findings in all these cases showed features of granular cell tumors confirming the diagnosis. Cases are reported for its rarity
and uncommon presentation.
drfariha06@yahoo.co.ukJ Clin Exp Pathol 2018, Volume 8
DOI: 10.4172/2161-0681-C2-049