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Journal of Alzheimers Disease & Parkinsonism | ISSN: 2161-0460 | Volume: 8
October 19-20, 2018 | New York, USA
5
th
International Conference on
Parkinson’s disease and Movement Disorders
Integrative rehabilitation maintains cognitive function in patients with Mild AD and MCI: Case
studies
Valentin Bragin
Stress Relief and Memory Training Center, USA
Statement of the Problem:
The pathogenesis of Alzheimer’s disease (AD) remains unknown to this day. Over the past decade,
clinical treatment of AD went far beyond amyloid and Tau protein theories. The most successful treatment model for AD is
integrative. It combines all available modalities, including pharmacological and non-pharmacological. The purpose of this
study is to demonstrate the results of rehabilitative treatment in patients with Mild AD and mild cognitive impairment (MCI)
via utilization of a novel computerized program.
Methodology & Theoretical Orientation:
The theory behind this treatment is the notion that increased cerebral blood flow
is a highly modifiable factor as well as a crucial element in the treatment of people with dementia. Our computerized program
consists of the motor speed (MS) and reaction time (RT) registration. Among the registration parameters there are simple and
complex RT (SRT and CRT, accordingly) and working memory (i.e., numbers) RT (WMRT).
Findings:
We present 4 people with duration of therapy ranging from 4 to 8 years. In this group, the MMSE score, clock
drawing test, and verbal fluency (animals and letters) were stable for the whole period of treatment. The same stability was
noted for MS, SRT, CRT, and WMRT. Performance and errors across all tested categories remained stable for SRT and CRT for
the whole group, and for WMRT only in two patients.
Conclusion & Significance:
Stabilization of cognitive functions in patients with AD and MCI was achieved as a result of
utilization of the computerized program. Integrative rehabilitation is a feasible treatment option for dementia patients to
improve their quality of life until new effective medications and other approaches become available.
Biography
Valentin Bragin, MD/PhD, has his clinical expertise in evaluation and treatment of people suffering from memory loss, dementia and depression. Based on his
experimental and clinical experiences, he developed and implemented a rehabilitative protocol for patients with dementia. Results of this treatment protocol have
been presented at different conferences starting in 2000. Simultaneously, a computerized program was designed to track treatment progression. The focus of his
experimental work in Russia was ontogenetic changes in various types of muscle proteins (i.e., cardiac and skeletal muscle tissue). He also studied the effects of
different types of hypoxia, including several types of physical trauma and ischemia of a lung lobe section. In the United States, he studied the induction of cortical
β-APP in the brain of a rat as a result of subcortical innervation loss. His passion lies in improving the quality of life and preventing cognitive decline in people with
dementia.
val11235@gmail.comValentin Bragin, J Alzheimers Dis Parkinsonism 2018, Volume 8
DOI: 10.4172/2161-0460-C6-052