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Volume 7
Journal of Pain & Relief
ISSN: 2167-0846
Pain Management 2018
October 11-12, 2018
October 11-12, 2018 | Zurich, Switzerland
7
th
International Conference and Exhibition on
Pain Research and Management
Use of a spinal cord stimulation lead for electromagnetic spectral analysis in 6 radiculopathy suffering
patients versus control
Damien Haton-Pietrin
and
Alexandra Dubreuil
Neuromodulation Fundamental Physics Laboratory, France
Statement of the Problem
: The Spinal Cord (SC) electromagnetic physics remains partially unknown despite extensive studies
[1]. Especially during chronic pain involving radiculopathy(R). The spectral pattern of the EM activity of the SC could be
explored to be more precise for Spinal Cord Stimulation (SCS) processing and to developing close loop device with machine
learning. Also, this study is based on the theoretical EM Thomson’s theorem [2-3] which said: an electrically charged EM
domain creates an EM equilibrium with electroneutral domain. Also, was postulate that a SCS electrode (SCSe, Octrode,
ABBOTT SJM) could be used as diagnostic device for SC EM [3] spectral analysis. The electro neutrality (EN) of SCS(e) was
preserved by plastic introducer.
Methodology:
After Ethic Committee and written patient’s consents, were included 6 patients who underwent SCS for L4-L5
R relief. Was defined as control the study of the signal issuing of 2 level up of SC (i.e. L2-L3). SCSe was connected to computer
(Apple, USA) for oscilloscopic high sensibility recording (MATLAB Signal Processing®) [3]. After obtaining SCSe EN, SCSe
was implanted with the classical percutaneously technic (PCT). Patients were under general anesthesia to avoid muscular
interferences during PCT. When the plastic introducer was implanted in epidural space, SCSe was also introduced to set the
first metallic contact in epidural space to record SC signal. Noise was subsequently susbtraced. Were first recorded the signals
at control level. Secondarily the was studied the L5-S1level.
Results:
The results show the different spectral signals in function of the level of SC studied (figure). Statistical Analysis [5]
were performed with JMP®software (SAS, USA). No significant difference between control signal in R suffering patients was
observed (Kolmogorov-Smirnov test) p>0,5. A statistical difference was observed between L4-L5 signals and control level
(ANOVA, p<0,0001). L4-L5 levels demonstrated a large spike amplitude of SC signal. It could be discussed that SCSe could
serve as diagnostic tool in chronic pain. Several clinical trials must be performed to confirm these results.
Recent Publications:
1. György Buzrzaâki, Costas Anastssou, Cristoph KochThe origin of extracellular fields and currents-EEG,ECoG,LFP ans
spikes, Nature Rev Neuroscience, 13, 407-420(2012).
Damien Haton-Pietrin et al., J Pain Relief 2018, Volume 7
DOI: 10.4172/2167-0846-C1-020
Figure:
Left rows: L4-L5 radiculopathy (R) signals, Right rows: L2-L3 Control signal (C): The R signal demonstrated different
spike amplitude (R) in contrast with C signal showed no significant spike.