otolaryngology-2017-scientifictracks-abstracts

9 / 14

Page 24
Notes:
conferenceseries.com
Volume 7, Issue 5 (Suppl) Otolaryngol
ISSN: 2161-119X Otolaryngol, an open access journal Otolaryngology 2017
October 18-19, 2017
October 18-19, 2017 Dubai, UAE
4th International Conference on
Rhinology and Otology
Topical hyaluronic acid in rhinitis medicamentosa: Could our perspective be changed?
Manuele Casale
Campus Bio-Medico University, Italy
Background&Aim: is study was designed to prospectively evaluate the role of nebulized hyaluronic acid (HA) as a treatment
for patients with rhinitis medicamentosa (RM). RM is a pathological condition of the nasal mucosa induced by prolonged,
excessive or improper use of topical decongestants.
Methods: Twenty- ve (25) patients were treated with HA nebulized via Spray-sol twice a day (morning and evening) for 10-
days (T1). Subsequently, a er three days of washout, patients were treated with physiological saline nebulized via Spray-sol
twice a day (morning and evening) for 10 days (T2).
Results: e HA Spray-sol treatment group signi cantly improved visual analogue scale (VAS) scores, whereas there
was no statistically signi cant di erence in the saline Spray-sol treatment group, results con rmed by the anterior active
rhinomanometry (AAR) data. An improvement in the Global Rhinitis Score (GRS) was recorded in both groups, but plus in
HA Spray-sol treatment group. Both groups showed a signi cant reduction in mucosal edema and nasal secretions. Patients
treated with HA Spray-sol reduced or even eliminated (11/25 patients) the use of topical decongestant within 10 days of
treatment with HA.
Conclusion: e results of this study suggest nebulized topical 9-mg sodiumhyaluronate plays a pivotal role in the management
of RM.
Biography
Manuele Casale has worked in Thomas Starzl Transplantation Institute in Pittsburgh, Humber River Hospital and the Hospital for Sick Children in Toronto, University
Hospital in Sofia and House Ear Institute in Los Angeles. He has attended the 20th Advanced Course of Surgical Anatomy and Dissection in Otology, the Course
of Surgical Anatomy, Microsurgery Intranasal Endoscopic Anterior Skull Base at the University of Zurich and Masters in Head and Neck Surgery at the National
Cancer Institute Regina Elena in Rome. He carries out research on several topics which include molecular biology, clinical research and innovative design tools
in otolaryngology.
Manuele Casale, Otolaryngol 2017, 7:5 (Suppl)
DOI: 10.4172/2161-119X-C1-022