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Volume 9
J Clin Exp Ophthalmol, an open access journal
ISSN: 2155-9570
Ophthalmology Summit 2018
February 26-27, 2018
February 26-27, 2018 | Berlin, Germany
19
th
Global Ophthalmology Summit
Metastatic Uveitis in oncological patients
Markosyan Armida Grishai
GVM Care and Research Medical Center, Russia
T
he purpose of this report is to describe atypical cases of metastatic uveitis in patients with a cancerous background, in the
sub clinical stage. Keeping in mind that the numbers of cancer patients are increasing with each passing year. Thorough
examination and cancer support of each patient who has applied to the doctor of any specialisation, in order to identify a
possibility of oncological diseases should become a practice in our day and age. In difficult cases, diagnostic specialists and
ophthalmologists are obliged to think about a possibility of atypical or complicated course malignant tumor. Doctors should
take it up on to them self as rule to fully examine the patient. This tactic is also applied in ophthalmology. Uveal tract of the
eye is a dense plexus of small blood vessels where most of them wash out inflammatory or neoplastic process. Imbalance in the
immune system is the basis for the pathogenesis of all inflammatory eye diseases, including uveitis, and nevertheless, diagnosis
- uveitis has an unclear etiology – it is not uncommon.
And now I would like to take a moment to give my own account of an observation obtained as a result of 5 years work at a
multidisciplinary medical center as an ophthalmology consultant.
Patient, 70 year of age, woman, was seeking first aid at our clinic with the following symptoms: weakness, headache, episodes
of confusion, clouded consciousness and short-termmemory loss, on a top of that red eye and blurred vision of OS for the past
2 weeks. Past ocular history was positive for high myopia, artiphakia and AMD moderate vision loss. On exam Visus OD
20/70 , OS 20/50 . Anterior segment examination of OS: Conjunctiva: positive for 3+ ciliary flush with a small subconjunctival
nodule adjacent to the limbus with surrounding engorged radiating vessels. Cornea: edema and folds in descemet shell, 1-2
corneal precipitates. AC: exudative suspension. Iris: an infiltration thickened with engorged adjacent stromal vessels. Posterior
synechiae formed superiorly at 7 o’clock. Gonioscopy: open angle with no neovascularization, inferior and inferonasal fluffy
material layered in the angle. Lens - artiphakia . Vitreous: destruction. She denies any known systemic malignancy; she
confirmed headaches, shortness of breath, weakness, and chronic fatigue during past year. The patient was sent for a CT
scan of chest and abdomen . CT scan results have showed a tumor in the region of the right adrenal gland, a tumor of the
left ovary, multiple metastases in the liver and peritoneal carcinomatosis. The tumor node biopsy confirmed ovarian cancer..
The patient was made PET CT to exclude metastasis in the uveal tract of the left eye. Eye metastasis was excluded, although
micrometastasis of the uveal tract remained under question? After 2 months her ocular lesion had regressed significantly along
with systemic improvement and local therapy of uveitis.
Biography
State Educational Institution of Higher Professional Education «I.M. Sechenov Moscow Medical Academy» of Ministry of Health of the Russian Federation. In 2004
she completed her Clinical residency in Scientific Research Institute of Eye Diseases of RAMS and in 2007, Academic fellowship in Scientific Research Institute
of Eye Diseases of RAMS.
markosyan_armida@mail.ruMarkosyan Armida Grishai, J Clin Exp Ophthalmol 2018, Volume 9
DOI: 10.4172/2155-9570-C1-078