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Journal of Obesity & Weight Loss Therapy | Volume: 08
August 28-29, 2018 | Paris, France
Obesity, Diet and Nutrition
17
th
International Conference on
Kennedy Adu-Twum et al., J Obes Weight Loss Ther 2018, Volume: 08
DOI: 10.4172/2165-7904-C5-069
Kennedy Adu-Twum
Kwame Nkrumah University of
Science and Technology, Ghana
A
claim on beta-glucans and maintenance of normal blood cholesterol
concentrations has already been assessed with a favourable outcome
(
AbuMweis et al., 2010, Keogh et al., 2003
). The main objective of this study was
to assess the claim of beta-glucan from barley grain products lowering effect on
low-density lipoprotein (LDL) and cholesterol among Ghanaian population.
Total cholesterol and LDL-cholesterol are the endpoints measures for this study.
Participants with elevated blood LDL-cholesterol concentration (≥ 3.8mmol/L)
were eligible for the intervention phase. The main study parameters were LDL-
cholesterol and total cholesterol. Out of a total of 343 participants recruited, 20.7%
(71/343) were diabetic while 8.75% (30/343) were pre-diabetic. Also, 63.64%
(217/343) had high total cholesterol levels, 32.46% (111/343) had high levels of
LDL and 27.57% (94/343) had high triglyceride. However, only participants with
high LDL (111) were selected for the intervention phase.
Many (43.59%) of the study participants were within the age range of 31-60 years.
During the baseline survey, 16.16% of the participants were diabetic, during the
2 weeks follow up, 12.12% were diabetic and 7.46% during the 4 weeks follow
up of daily administration of beta-glucan supplement. Also, the proportion of
participants with high TCHOL dropped from 95.96% to 78.79% and slightly
increased to 83.58% by follow-ups I and II respectively. The proportion of
participants with high LDL dropped from a baseline of value of 95.96% to 60.61%
and increased to 79.1% by follow-ups I and II respectively. Also, the proportion of
participants with desirable HDL dropped from 95.96% at baseline to 71.72% and
37.31% by follow-ups I and II respectively. The proportion of participants with
high TG at baseline was 34.34% and this has declined to 34.34% and increased
slightly to 32.84%by follow-ups I and II respectively. Beta-glucans has significantly
lowered blood cholesterol concentrations among Ghanaians.
Efficacy of beta-glucans from barley and maintenance of normal blood LDL-cholesterol concentrations: A
study case study in Ghana
Biography
Kennedy Adu-Twum has completed his MB ChB program at the age of 26 years from the Kwame Nkrumah University, Ghana, Faculty of Medicine. He is a Junior
Physician Health Staff at the Kumasi South Hospital of the Diagnosis Directorate of the hospital and has served for 2 years. He has published 13 papers in reputed
journals and has been serving as an editorial member for many heaths editorial programs in the country.
kennedy_adutwum@hotmail.comco-authors:
Denis Dekugmen Yar
and
Rose Adjei
University of Education Winneba, Ghana