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Volume 6, Issue 4(Suppl) J Obes Weight Loss Ther
ISSN: 2165-7904 JOWT, an open access journal
Page 45
Notes:
Obesity Congress 2016
August 08-10, 2016
conferenceseries.com
August 08-10, 2016 Toronto, Canada
6th World Congress on
Obesity
How did an albino patient lose 148 lbs of weight? A case report
Zarnain Shah1 , Samaneh A Motanagh2 and Syed Wajih Rizvi3
1Liaquat University of Medical & Health Sciences, Pakistan
2Ankara University School of Medicine, Turkey
3R-Endocrinology, USA
Introduction: Obesity is a highly prevalent and yet the most neglected disease. The number of overweight and obese people reached
2.3 billion and 700 million worldwide respectively, by the year 2015. Obesity is not a social disgrace but an actual disease with a major
genetic component to its etiology. Obesity treatment is a lifelong task. Weight reduction medications should be used as an adjunct
to diet restriction, exercise and behavioral modifications, when these measures alone have not resulted in adequate weight loss. We
hereby present a case of a morbidly obese male patient with occulocutaneous albinism who has lost 148 lbs of weight. Furthermore,
the report highlights the genetic link between occulocutaneous albinism and obesity.
Case Presentation: 28-year-old male with occulocutaneous albinism presented with 361.8 lbs of weight (BMI: 62.1) and complaint
of difficulty in losing weight. Physical examination revealed hypertension, low intelligence, gynecomastia and infantile testicles. Lab
investigations showed unregulated hyperlipidemia and hypotestosteronemia. The patient was prescribed Xenical (Orlistat) 120 mg.
Over the period of five years, he lost 83.8 lbs. After this time, Xenical’s effectiveness was significantly reduced. Consequently, the
patient was started on Victoza (Liraglutide) on which he lost 64 lbs in three years. Thus, a sum of 147.8 lbs of weight was lost without
any side effects of the drugs.
Discussion: Obesity needs to be treated within the healthcare system as any other complex disease. We observed Xenical and Victoza
to be safe and effective in reducing obesity. Substantial literature has emerged to show that in both Occulocutaneous albinism and
Prader-Willi syndrome (the most common genetic cause of obesity) the P-gene is mutated on Chromosome 15. This highlights the
genetic susceptibility of our albino patient for developing morbid obesity.
Conclusion: Obesity develops from the interplay of both genetic and environmental factors. This case clearly illustrates that Xenical
and Victoza can be safe and efficient for weight loss in a morbidly obese patient. Furthermore, scientific research in the genetic aspects
of obesity can help develop new strategies towards its prevention and treatment.
Biography
Zarnain Shah is a fourth-year Medical student at Liaquat University of Medical and Health Sciences, Jamshoro. Along with her extraordinary academic record, she holds a
keen interest for scientific research..
Zarnain Shah et al., J Obes Weight Loss Ther 2016, 6:4(Suppl)