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Volume 6, Issue 6 (Suppl) OMICS J Radiol, an open access journal
ISSN: 2167-7964 Neuroradiology 2017
October 30 to November 01, 2017
October 30 to November 01, 2017 | San Antonio, USA
2nd International Conference on
Neuroscience, Neuroimaging & Interventional Radiology
MRI to investigate the complexity of the CSF flows and its interactions with the cerebral blood flows
Olivier Baledent
Responsable De L’Unité De Traitement De L’Image Médicale, France
The rapid amplitude change of the cerebral systolic arterial input flow increases the brain volume. Then CSF is quickly displaced
out of the cranium toward the spinal canal; ICP increase is therefore limited. Nevertheless, this first CSF response is also limited
and must be supplemented with the cerebral blood venous outflow. The venous contribution is slower than the CSF but at the end
drains from the cranium all the blood input volume. Finally, due to the narrow aqueduct of Sylvius, a small CSF ventricular flows
out of the fourth ventricle. Cerebral hydrodynamics knowledge has benefited considerably from the introduction of phase-contrast
magnetic resonance imaging (PCMRI), the unique technique to investigate the small but rapid CSF oscillations. Using post-processing
software, key parameters of flow can be easily calculated. In ten minutes, CSF flow is quantified in the spinal subarachnoid spaces, the
pontine cistern, the foramens of Magendi and the aqueduct of Sylvius. Blood flow is quantified in the internal carotid and the vertebral
arteries, straight and sagittal sinus, jugular and epidural veins. These flows data can be functional information’s complementary to
the morphological imaging to better investigate the cranio-spinal system in case of patients presented with hydrocephalus, chiari
malformation, syringomyelia, cerebral hemorrhage, intracranial hyper or hypo tension. The objective of this presentation is to
describe the power and the limit of such clinical 2D PCMRI protocol concerning CSF and blood flow investigations and present what
we have found in different healthy and pathological populations.
Biography
Olivier Baledent did his PhD in the area of Biophysics & Radiology and is currently working as an Assistant Professor in Amiens 'University Hospital in France. He is heading
the Medical Image Processing Department and BioFlowImage ) research team. After a Master’s degree in Informatics in Amiens, he passed a Post-graduate
diploma in the field of Image Processing in Lyon. He passed his PhD in 2001 at Jules Verne University. The thesis subject was already about CSF flow imaging using MRI
technique. Now inside Amiens 'University Hospital, with clinicians he continues to develop CSF research and applies non-invasive hydrodynamic approach in clinical prac-
tice. He is also Biophysics' Teacher at the Medical School of Amiens.
Olivier Baledent, OMICS J Radiol 2017, 6:6, (Suppl)
DOI: 10.4172/2167-7964-C1-018