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Volume 6, Issue 6 (Suppl) OMICS J Radiol, an open access journal
ISSN: 2167-7964 Neuroradiology 2017
October 30 to November 01, 2017
October 30 to November 01, 2017 | San Antonio, USA
2nd International Conference on
Neuroscience, Neuroimaging & Interventional Radiology
Kwo-Whei Lee, OMICS J Radiol 2017, 6:6, (Suppl)
DOI: 10.4172/2167-7964-C1-018
Cerebral venous dynamics change as potential indication of cerebral aneurysmal rupture
Kwo-Whei Lee
Chang-Hua Christian Hospital, Taiwan
Taipei Medical University, Taiwan
Introduction: Many inconsistent etiologies of cerebral aneurysmal rupture including a wide spectrum of factors have been reported.
Our recent observation discloses the potential new factor of cerebral aneurysm rupture with cerebral venous pressure gradient.
Materials and Methods: We retrospectively reviewed 25 cases treated with coil embolization with or without cerebral aneurysmal
rupture. Seven males and 18 females were recruited in this study. The age ranging from 49 to 71 and average being 59.Quantitative
color-coded cerebral angiography was performed during coil therapeutic procedures to measure cerebral venous circulation.
Result and Conclusion: Ruptured cases had shorter and symmetrical cerebral venous circulation time (P <0.05). In addition, an
asymmetrical venous outflow pattern was critical for aneurysmal rupture as seen in case 1. Non-ruptured cases tended to have slower
and asymmetrical cerebral venous circulation compared with rupture cases as seen case 2. Symmetrical and shorter cerebral venous
circulation in the epislateral dysplasia venous outlet may be a potential new factor for cerebral aneurysm rupture. An asymmetrical
venous outflow pattern was critical for managing cerebral aneurysm and determines aneurysmal rupture.
Illustrative Case: Case 1: A 50 year old male presented with acute anterior communicating saccular aneurysm ruptured and treated
by endovascular coiling immediately post Dyna CT study. He discharged without any sequelae but still just mild headache. The venous
phase showed atresia of left dural venous sinus, right dural venous sinus is dominated venous drainage but there is symmetrical
venous flow. Post-Postcoiling showed the arterial flow had no change but delayed venous flow. This symmetrical venous flow might
indicate increasing venous pressure gradient.
Case2: A 64 year old female had asymptomatic non-ruptured Rt distal internal carotid small wide neck saccular aneurysm
Result and Conclusion: Cerebral venous circulation time among rupture and non-rupture patients:
Non-rupture: Right ΔCCT:11.32+/-88 Left ΔCCT:12.49+/-42
Rupture: Right ΔCCT:11.12+/-1.87 Left ΔCCT:11.54+/-2.22
Ruptured cases had shorter and symmetrical cerebral venous circulation time (P <0.05). In addition, an asymmetrical venous outflow
pattern was critical for aneurysmal rupture as seen in case 1. Non-ruptured cases tended to have slower and asymmetrical cerebral
venous circulation compared with rupture cases as seen case 2. Symmetrical and shorter cerebral venous circulation in the epislateral
dysplasia venous outlet may be a potential new factor for cerebral aneurysm rupture. An asymmetrical venous outflow pattern was
critical for managing cerebral aneurysm and determine aneurysmal rupture.
Biography
Kwo-Whei Lee is currently working in Department of Medical Imaging, Vascular and Genomic Research Center, Changhua Christian Hospital; Taipei, Taiwan. He is also
engaged in Imaging Research Center, Taipei Medical University; Taipei, Taiwan