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Clinical Microbiology: Open Access | ISSN: 2327-5073 | Volume: 7
Microbiology: Education, R&D and Market
7
th
Annual Summit on
September 28-29, 2018 | San Antonio, USA
Antibiotic resistance: A global threat
Vichal Rastogi
Sharda University, India
Statement of the problem:
Antimicrobial resistance is an under-appreciated threat to public health in nations around the globe.
With globalization booming, it is important to understand international patterns of resistance. The effectiveness of many antibiotics
is decreasing due to its extensive use for over a decade or two. This has led to an increase in the number of bacterial strains acquiring
resistance to these antibiotics. When pathogenic microorganisms can multiply beyond some critical mass in the face of invading
antimicrobials, treatment outcome is compromised; this phenomenon is referred to as antimicrobial resistance (AMR).
Methodology &Theoretical Orientations:
The retrospective study was carried out in a teaching hospital, Greater Noida to determine
the prevalence of multidrug resistance in patients in relation to empirical antibiotic therapy in the hospital. Various samples (pus,
urine, blood) were collected for bacterial culture and antibiotic sensitivity. Total 476 bacterial strains were taken in these studies
which were isolated from ICU, surgery, obstetrics & gynecology and orthopedics. The 56 bacterial isolates were found to be resistant
to multiple drugs. The 29 (51.78%) of resistant bacteria were prevalent in ICU, 12(21.42%) in Gynaecology,10(17.85%) in Surgery,
05(8.92%) in Orthopedics and were studied for their antibiotic sensitivity pattern. The highest numbers of resistant bacteria were
Staphylococcus aureus i.e. 15(26.78%) cases followed by 13(23.21%) of
Pseudomonas
sp., 10(17.85%) of
Proteus vulgaris
, 09(16.07%)
of
Escherichia coli
, 08(14.28%) of
Klebsiella
sp. and 01(1.78%) of
Citrobacter
sp. All the bacterial strains were resistant to common
antibiotics like Penicillin, Amoxicillin, Doxycycline & Cotrimoxazole and some were even resistant to Imipenem. Therefore we have
outlined the nature of the antimicrobial resistance problem as an important health and cost issue for the national and international
community.
drvichal@yahoo.comClin Microbiol 2018, Volume: 7
DOI: 10.4172/2327-5073-C3-040