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Volume 7, Issue 6 (Suppl) J Bacteriol Parasito
ISSN: 2155-9597 JBP, an open access journal Microbiology 2016
November 28-29, 2016
November 28-29, 2016 Valencia, Spain
7th World Congress on
Microbiology
Young Ah Kim et al., J Bacteriol Parasitol 2016, 7:6 (Suppl)
Community associated extended spectrum β lactamase producing Escherichia coli infection in Korea
Young Ah Kim1, Yee Jeong Kim1 and Heejung Kim 2
1National Health Insurance Service Ilsan Hospital, South Korea
2Yongin Severance Hospital, South Korea
Background: The community associated infections due to extended spectrum β lactamase (ESBL) producing Escherichia coli has
been well known clinical problems. Serogroup O25-multilocus sequence typing (MLST) sequence type ST131 E. coli has been known
as a major clone for worldwide spread because of its multidrug resistances and higher virulence traits.
Methods: The recent extent and significance of community associated infections caused by ESBL producing E. coli were evaluated by
a prospective observational study. We collected non-duplicated E. coli isolates, isolated from consecutive, sequentially encountered
patients with community onset episodes (either outpatients or within 48 hours of admission) between March and April 2016 in
two community hospital in Gyeonggi province, Korea. Sites of acquisition of the organisms (community associated or healthcare
associated), antimicrobial susceptibility and PCR of O25/O16 genes to screen global epidemic ST131were evaluated.
Results: Of 213 patients infected or colonized with E. coli as outpatients or within 48 hours of hospitalization, 119 (55.9%) had
community associated infection (65.5% of which represented urinary tract infection), while the remainder had healthcare associated
infection. Of the community associated infections, 26.9% (32/119) were caused by the globally epidemic ST131 strain (25/119 for
O25-131 and 7/119 for O16-ST131 respectively). ESBL production was confirmed by phenotypic methods in 24.4% (29/119) of the
community associated infections.
Conclusions: A considerable portion of community onset, ESBL producing E. coli infections now occur among patients in Gyeonggi
Province, Korea. Increase of ST131 E. coli infections in community without healthcare associated risk factors could be worrisome
public health threats.
Biography
Young Ah Kim is a Researcher at the Department of Laboratory Medicine, National Health Insurance Service Ilsan Hospital, South Korea.