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conferenceseries
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Volume 5, Issue 3 (Suppl)
J Infect Dis Ther, an open access journal
ISSN:2332-0877
Infectious Diseases 2017
August 21-23, 2017
3
rd
Annual Congress on
Infectious Diseases
August 21-23, 2017 San Francisco, USA
Lowprevalence of hepatitis B andCamong tuberculosis patients inDuhok Province, Kurdistan:AreHBsAg
and anti-HCV prerequisite screening parameters in tuberculosis control program?
Muayad A Merza, Safer M Haji, Abid Mohialdeen Hasan Alsharafani
and
Shivan U Muhammed
University of Duhok, Kurdistan Region, Iraq
Objective/Background:
Viral hepatitis, particularly hepatitis B virus (HBV) and hepatitis C virus (HCV), infections and
tuberculosis (TB) are a global public health concern. Co-infection with HBV or HCV among TB patients may potentiate the
risk of hepatotoxicity induced by anti-TB drugs. Hence, the aim of this study was to identify the prevalence of HBV and HCV
among TB patients included in the Duhok National Tuberculosis Program (NTP).
Methods:
The Duhok NTP Center is a specialized institution in Duhok City, Iraq, concerned with management and follow-
up of TB patients. A cross-sectional study was conducted at the center between June 2015 and May 2016. All documented TB
patients were analyzed on the basis of sociodemographic and other characteristics. Thereafter, all patients underwent screening
for hepatitis B surface antigen (HBsAg), anti-HCV, and anti-HIV using enzyme-linked immunosorbent assay (ELISA). The
results obtained were analyzed by entering the data in binary format into a Microsoft Excel spreadsheet. A p value of <.05 was
considered to be statistically significant.
Results:
Two-hundred fourteen (214) documented TB patients were recruited in this study, with 127 (59.3%) males and 87
(40.7%) females. The mean age of the patients was 40.34 years (±20.29). Of the total number of patients, 4 cases (1.8%) were
HBsAg-positive and one case (0.9%) was positive for anti-HCV. The variables significantly associated with HBV were history
of surgical dental procedure [odds ratio (OR), 0.04; 95% confidence interval (CI), _0.01 to 0.04; p=.03], and nationality (OR,
13.67; 95% CI, 0.46–210.85; p=.007).
Conclusion:
The prevalence of HBV and HCV co-infection among TB patients in this study was low. This may be explained
by the low rate of blood transfusion among the patients, and the very low prevalence of HIV.
muayad.merza@uod.acJ Infect Dis Ther 2017, 5:3 (Suppl)
DOI: 10.4172/2332-0877-C1-027