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Volume 6 Journal of Infectious Diseases & Therapy
ISSN: 2332-0877 Infection Prevention 2018
December 06-07, 2018
Page 43
Notes:
conferenceseries.com
December 06-07, 2018 | Valencia, Spain
14th World Congress on
Infection Prevention and Control
Sharad Kumar Yadav, J Infect Dis Ther 2018, Volume 6
DOI: 10.4172/2332-0877-C6-052
Recent advances in phage display technology
Emergence of prokaryotic and eukaryotic expression system for the use of antibody production in the beginning years of 1980s was
a surprise entry for the new era of ‘IMMUNOTECHNOLOGY’ [a branch of biotechnology that employs sets to bio-technique for
the production of immunobiologicals]. Entry of phage display system during the years of 1990s for the antibody fragment expression
has been created a bigger achievement and turned into a milestone, which concludes the method of phage display technology for the
production of small fragments of antibodies that must possess the quality and the characteristic of binding to the antigens specifically
which are popularly and most commonly known as Nanobodies. Phage display technology is a simpler, less time consuming and
more efficient approach than the conventional methodology of the antibody production, which contains a number of component
for the production of small fragment specific antibodies that includes the target or the antigen in anticipation to the ligand or binder
or the antibody which are meant to be produced, next to this it concludes a Phage Display Library, A Phage system, Appropriate
Selection or screening process, Appropriate Expression and purification system. The most common bacteriophages used are M13,
and FD filamentous phage, though T4, T7 and λ Phage have also been used in some cases.
Biography
Sharad Kumar Yadav has 28 years of teaching and research experience and has served to various senior positions of the University including Registrar of the DUVASU
University. He is currently Professor, Head of Department of Veterinary Microbiology, and Director at Cow Research Institute at DUVASU, Mathura India. He has published
number of papers in reputed International & National journals and has a vast experience in the arena of BHV-I virus.
Sharad Kumar Yadav
Veterinary University, India