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November 28-29, 2016 Valencia, Spain
4th World Congress on
Infection Prevention and Control
Volume 4, Issue 8 (Suppl) J Infect Dis Ther 2016
ISSN: 2332-0877, JIDT an open access journal Infection Control 2016
November 28-29, 2016
Persistence of low levels of plasma viremia and of the latent reservoir in patients under ART: A fractional
order approach
Carla M A Pinto
Polytechnic of Porto, Portugal
Low levels of viral load are found in HIV infected patients, after many years under successful suppressive anti-retroviral therapy
(ART). The factors leading to this persistence are still under debate but it is now more or less accepted that the latent reservoir
may be crucial to the maintenance of this residual viremia. In this talk, we focus on the role of the latent reservoir in the persistence of
the latent reservoir and of the plasma viremia in a fractional order (FO) model for HIV infection. The proposed model provides new
insights on the role of the latent reservoir in the persistence of the latent reservoir and of the plasma virus. To our best knowledge, this
is the first FOmodel that deals with the role of the latent reservoir in the persistence of low levels of viremia and of the latent reservoir.
Biography
Carla MA Pinto is an Adjunct Professor at School of Engineering, Polytechnic of Porto, since December 1997. She is a Researcher at Center for Mathematics of the
University of Porto, since 2003. She has completed her PhD degree in Mathematics in 2004. Her current research fields involve the study of epidemiological models
for several diseases, namely HIV/AIDS, tuberculosis, malaria, amongst others. She also studies coupled nonlinear dynamical systems, considering fractional and
integer derivatives using bifurcation theory and symmetry techniques. She has authored/co-authored a large number of research papers, published in reputed
international journals and international conferences. She has been serving as an Editorial Board Member of several journals. She is the Sub-Director of the
Department of Mathematics since 2012.
Carla M A Pinto, J Infect Dis Ther 2016, 4:8 (Suppl)