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.com
Volume 6
Journal of Infectious Diseases and Therapy
ISSN: 2332-0877
Infection Congress 2018
March 01-02, 2018
March 01-02, 2018 Berlin, Germany
5
th
International Congress on
INFECTIOUS DISEASES
Effectiveness of SUT-OVCCA-Mobile application for risk group screening of a carcinogenic liver
fluke among rural population in Thailand
Natthawut Kaewpitoon
Suranaree University of Technology, Thailand
L
iver fluke caused by Opisthorchis viverrini is an endemic in Southeast Asia particularly in Thailand, Lao People’s
Democratic Republic, Cambodia and central Vietnam. The infection is associated to cholangiocarcinoma; bile duct cancer.
Active surveillance in rural communities with an appropriate low-cost screening tool is required to facilitate early detection.
Previously, we developed verbal screening test and then created for smartphone. In addition, mini-parasep sf parasite faecal
concentrator is a new technique that increased the sensitivity and specificity for helminthic infection. This study aimed to
screen the risk group for liver fluke infection among participants from rural communities northeast areas of Thailand where
has been reported the highly incident of cholangiocarcinoma, by using OVCCA mobile application (verbal screening test), and
determine the liver fluke infection in the high risk group by using mini-parasep sf parasite faecal concentrator (mpfc). A cross-
sectional survey was performed among 560 participants from Nakhon Ratchasima, Chaiyaphum, and Khon Kaen province,
northeast Thailand during October 2016 and February 2017. All participants were self-screened test through OVCCA mobile
application and then reported the result for themselves and data retrieved. The high risk group was asked for faecal collected
and parasitic examined by using mpfc. The majorities of participants were female (58.3%), age group 41-50 years old (37.3%),
primary school (61.0%), and agriculture (84.4%). The data demonstrated OVCCA application had a very good intra-class
correlation coefficients =0.895 and could clearly distinguish the risk group of liver fluke infection. The item analysis was
weighted and found that cyprinoid fish consumption had an important weight for liver fluke infection screened (β=0.427,
t=409.892, p=0001), and partial correlation=0.967. Participants had scores with the low risk; however, the high risk was found
3.1%. In the high risk group found that the liver fluke infection rate was 2.8%, found frequently in male, primary school, and
agriculture group. In conclusion, liver fluke is still a serious problem in community level of Thailand. OVCCA application is
a valid and reliable method for assessing liver fluke risk among community populations therefore it may be useful for early
detection in other epidemic areas of Thailand.
Biography
Natthawut Kaewpitoon completed his PhD from Khon Kaen University in Thailand and molecular biology practicum performed at Queensland Institute of Medical
Research, Brisbane, Australia. He is the committee member of Parasitic Disease Research Center, Institute of Medicine, Suranaree University of Technology,
Thailand. He has published more than 60 papers in reputed journals and has been serving as an Editorial Board Member of repute Natthawut Kaewpitoon completed
his PhD from Khon Kaen University in Thailand and molecular biology practicum performed at Queensland Institute of Medical Research, Brisbane, Australia. He
is the committee member of Parasitic Disease Research Center, Institute of Medicine, Suranaree University of Technology, Thailand. He has published more than
60 papers in reputed journals and has been serving as an Editorial Board Member of repute.
natthawut.ka@sut.ac.thNatthawut Kaewpitoon, J Infect Dis Ther 2018, Volume 6
DOI: 10.4172/2332-0877-C1-039