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conferenceseries
.com
Volume 5, Issue 2 (Suppl)
J Infect Dis Ther 2017
ISSN: 2332-0877, JIDT an open access journal
Infection Congress 2017
May 11-12, 2017
May 11-12, 2017 Barcelona, Spain
4
th
International Congress on
Infectious Diseases
Infection and colonization due to
Achromobacter xylosoxidans
in an intensive care unit: Role of endoscopes
Zoher Kadi
2
, Bénédicte Nguon
1
, Jack Richecoeur
1
, Danielle Combeaux
1
, Edith Baticle
1
and
Noëlle Vidal
1
1
Beauvais Hospital Center, France
2
CCLIN Paris Nord, France
Background & Aim:
In 2015, our hospital acquired infection (HAI) surveillance system detected unexpected and rare pulmonary
infections and colonizations due to
Achromobacter xylosoxidans
(Ax) among patients hospitalized in the intensive care unit (ICU)
of our 600-bed hospital. A pulmonary endoscopy had been performed on most of those patients. In order to break the transmission
chain, we conducted an investigation to identify the potential source for the infections.
Material & Methods:
A case definition was completed and all medical records of cases were reviewed with the ICU medical staff.
Audits were conducted on endoscopy procedures, hand hygiene compliance (HHC) and laboratory procedures. In addition to that,
an audit was carried out to assess the safety level of endoscopes disinfection procedures. Samples were obtained from the ICU
environment (water, antiseptics and surfaces) in addition to samples of all the endoscopes used during the concerned period. Ax
strains were sent to the National Reference Laboratory. Finally, a case-control study aiming to find risk factors was conducted.
Results:
Between 09/2013 and 08/2014, six infections and 10 colonizations were diagnosed. All environmental samples were negative
for Ax, but samples taken from the sinks and taps were positive for
Pseudomonas aeruginosa
. The samples of endoscopes, antiseptics
and surfaces were all negative. The HHC audit revealed poor compliance among health care workers. The case-control study clearly
showed that an endoscope was associated with the presence of Ax (p<10-3).
Conclusion:
After removal of this endoscope, no further cases were diagnosed. In this outbreak, no Ax strain was isolated from the
endoscopes or in the ICU environment and the case-control study was critical in ending the episode. This study therefore showed the
importance of obtaining reliable data to conduct the case-control study and the need for good traceability of these data.
Biography
Zoher kadi is currently working as an expertise in Picardie regional center for nosocomial infections control. She has published numerous research papers and
articles in reputed journals and has various other achievements in the related nosocomial studies. She has extended his valuable service towards the scientific
community with his extensive research work.
be.nguon@ch-beauvais.frZoher Kadi et al., J Infect Dis Ther 2017, 5:2 (Suppl)
http://dx.doi.org/10.4172/2332-0877-C1-023