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Volume 5, Issue 2 (Suppl)

J Infect Dis Ther 2017

ISSN: 2332-0877, JIDT an open access journal

Infection Congress 2017

May 11-12, 2017

May 11-12, 2017 Barcelona, Spain

International Congress on

Infectious Diseases

Depression improvement among patients with HIV and endocrine dysfunction after hormone therapy

Fereshteh Ghiasvand, Ladan Abbasian, Afarin Rahimi-Movaghar, Alireza Esteghamati, Mehrdad Hasibi

and

Nahid Zakerzadeh

Tehran University of Medical Sciences, Iran

Background:

Endocrine diseases are common among men living with HIV (MLWH) known as curable etiology of depression.

Depression impedes adherence to treatment and perceived quality of life.

Aim:

The objective of this study was to evaluate depression after medical treatment of underlying endocrine diseases among Iranian

MLWH.

Materials & Methods:

We recruited a convenient sample of 296 MLWH at a referral HIV clinic from April 2013 to March 2014. In

phase I (cross-sectional evaluation), all patients were interviewed using the beck depression inventory (BDI- II) questionnaire. In

phase II, participants with moderate to severe depression (n=110, scores ≥21) were evaluated for endocrine diseases (evaluations:

total testosterone, triiodothyronine, thyroxine, thyroid stimulating hormone, luteinizing hormone, follicle stimulating hormone

and serum cortisol). 11 patients diagnosed with hypogonadism were finally considered for hormone replacement therapy. We re-

evaluated changes in depressive symptoms with BDI-II.

Results:

From237 participants, 136 (75%) hadBDI scores ≥21; 110 participated in the endocrine evaluations. Secondary hypogonadism

(total testosterone ≤2.8 nmol/l; LH, FSH: normal) was the only observed abnormality in 10% (n=11) of the patients and hormone

replacement was prescribed to seven of them for three months. All patients were re-evaluated for depression; significant changes were

observed in final scores (p=0.027).

Conclusions:

Evaluation and treatment of hypogonadism can help clinicians to reduce or control depression among people living

with HIV; hence improving treatment compliance and patient outcomes.

Biography

Fereshteh Ghiasvand is an Assistant Professor of Infectious Diseases department at Tehran University of Medical Sciences.

Fereshteh Ghiasvand et al., J Infect Dis Ther 2017, 5:2 (Suppl)