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Industrial Microbiology 2016
October 17-18, 2016
Volume 8, Issue 5(Suppl) J Microb Biochem Technol
ISSN:1948-5948 JMBT, an open access journal
conferenceseries .com
October 17-18, 2016 Kuala Lumpur, Malaysia
Industrial & Pharmaceutical MicrobiologyInternational Conference and Summit on
Hanan Moawia Ibrahim, J Microb Biochem Technol 2016, 8:5(Suppl)
Isolation and characterization of thermophilic Streptomyces sp. with potential production of actinokinase
Hanan Moawia Ibrahim
Ministry of Higher Education & Scientific Research, Sudan
The study aimed to produce a potent fibrinolytic enzyme actinokinase from local isolate in batch fermentation, culture
of identified thermophilic Streptomyces spp. grown on glucose yeast extract peptone medium pH of 8.0. The hemolytic
activity of the crude enzyme and time spend for complete lysis was tested using blood agar media and test tubes containing
clotted blood. The in vivo clot lysis of the crude enzyme was found to be faster (20 minutes) compared to the other commercial
fibrinolytic enzyme (90 minutes). The enzyme was stable at a broad range of pH ranging from 5 to 9. The thrombolytic potential
of this particular isolate indicated that it could extract a promising actinokinase with potent activity.
Biography
Hanan Moawia Ibrahim has completed her PhD from UKM (Malaysia) at School of Bioscience and Biotechnology. She is the Deputy Director of Central Laboratory,
Sudan. She has published more than 20 papers in reputed journals and has been serving as an Editorial Board Member of repute for the followings international
peer-reviewed journals: Asian Journal of Biological Sciences, Asian Journal of Biochemistry, Asian Journal of Biotechnology, Research Journal of Microbiology and
Pakistan Journal of Biological Science.