Page 27
Industrial Microbiology 2016
October 17-18, 2016
Volume 8, Issue 5(Suppl)
J Microb Biochem Technol
ISSN:1948-5948 JMBT, an open access journal
conferenceseries
.com
October 17-18, 2016 Kuala Lumpur, Malaysia
Industrial & Pharmaceutical Microbiology
International Conference and Summit on
Luis AMaldonado et. al., J Microb Biochem Technol 2016, 8:5(Suppl)
http://dx.doi.org/10.4172/1948-5948.C1.022Morphological traits of some actinobacteria and their importance in the genomic era
Luis A Maldonado
1,2
and Erika T. Quintana
3
1
Universidad Autonoma Metropolitana, Mexico
2
Universidad Nacional Autonoma de Mexico, Mexico
3
Instituto Politécnico Nacional (IPN), Mexico
M
icrobes still are a vast and fully unexplored source for novel biologically active compounds and the actinobacteria subgroup
(Gram positive bacteria with a 40 to 60% GC content) accounts for nearly 80% of the current medically employed
antibiotics. Among the actinobacteria, members of the genus
Salinispora
are a promising source for novel compounds due to
their unique ability to solely grow on the presence of sea water, a fact which supports their adeptness to the marine ecosystem.
Salinispora
are still difficult to isolate and characterize as strains usually undergo several chameleonic morphological states. In
this study, a collection of 66 isolates recovered from a national resource and assigned to the genus
Salinispora
were screened
for their metabolic profiles coupled to both genotypic and morphological properties. Evaluation of the enzymatic profile of the
strains for amylases, cellulases, lipases and proteases indicated that all the strains produced amylases and lipases whereas only
7.5% produced proteases; no cellulase activity was found. Also, the 66 strains showed antimicrobial activity against clinical
isolates of
Staphylococcus epidermidis
. It is therefore, proposed that genome sequencing, single gene oriented phylogenies
and morphological properties should be used in conjunction to construct a robust system to fully comprehend and exploit
the biotechnological potential of
Salinispora
since several of the isolates from this study contained sequences not-related to
previously reported Rifamycin clusters from
Salinispora
recovered from other regions of the world.
Biography
Luis A Maldonado has completed his PhD at the University of Newcastle, UK in 2002, followed by a Postdoctoral position in Biodiversity and Biogeography
of Marine Actinomycetes. He has published more than 30 papers and/or book chapters in the actinobacteria field that have been cited over 1250 times. He is
PLOS ONE Academic Editor, constantly reviews manuscripts for other journals and grant funding agencies. He is also a co-author on the latest edition of the
Bergey’s Manual
for the genera
Gordonia, Nocardia
and
Salinispora
. His research interests are in improving selective isolation strategies for industrially important
actinobacteria notably
Micromonospora
,
Salinispora
and rare
Streptomyces
while exploring their biotechnological applications.
lmaldonado@correo.uam.mx