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Volume 8, Issue 10 (Suppl)

J Diabetes Metab

ISSN: 2155-6156 JDM, an open access journal

Herbal Diabetes 2017

November 02-04, 2017

November 02-04, 2017 Bangkok, Thailand

International Conference on

Herbal and Alternative Remedies for

Diabetes and Endocrine Disorders

Comparison of anxiolytic effects of the homeopathic complex vita-C 15 in comparison with

Aconitum

napellus

in the acutely stressed C57BL6 mice

Charis Liew Siaw Min

Cyberjaya University College of Medical Sciences, Malaysia

nxiety, phobias and stress are the main mental health problems among the Malaysian population, with global prevalence

varying from 8% to 18%. Even so, less than 30% who suffer these disturbances seek treatment. The objective of this study is

to evaluate and compare the anxiolytic effects of

Aconitum napellus

and Homeopathic complex vita-C 15 in the acutely stressed

C57BL6 mice by using the fecal corticoid test, Open Field Test (OFT) and c-fos, NMDAR 2B, NPY 1R and NPY 2R activity

through the hippocampus. A double blinded randomized controlled study is conducted at Animal Laboratory of Cyberjaya

University College of Medical Sciences (CUCMS). All the animals are acclimatized to constant laboratory conditions for 14

days before starting the experiments. Prior to the experiment, a pilot study is performed to identify the most suitable and

ideal potency for the homeopathic remedy of

Aconitum napellus

. The animals are tested (n=3) per group on the potency of 6

C, 30 C and 200 C. The treatments are carried out over 9 days. 48 male C57BL6 mice (n=6), 4-5 weeks of age are used. They

are randomly selected and divided into two groups. Group-I is the healthy control group of mice which are not exposed to

acute stress. Group-II (stress group) comprise of mice expose to acute restraint stress. Prior to restraint stress, the treatments

given are

Aconitum napellus

30 cH, Homeopathic complex vita-C 15, Diazepam and placebo. Then the results are evaluated

by fecal CORT test and open field test by comparing the anxiolytics between pre-test and post-test.

Aconitum napellus

30 cH

and Homeopathic complex vita-C 15 are expected to be more effective and can reduce the occurrence of anxiety in the acutely

stressed C57BL6 mice. Thus, research into prevention and supportive therapies is necessary and beneficial for this disorder.

J Diabetes Metab 2017, 8:10 (Suppl)

DOI: 10.4172/2155-6156-C1-073