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conferenceseries
.com
Volume 7, Issue 10 (Suppl)
Gynecol Obstet (Sunnyvale), an open access journal
ISSN: 2161-0932
Gynecology 2017
October 02-04, 2017
4
th
International Conference on
Gynecology & Obstetrics
October 02-04, 2017 Barcelona, Spain
The Effect Of Nifedipine UsedAs TocolyicAgent On PostpartumBlood LossAmong Filipino Pregnant
Patients In ATertiary Hospital: A Prospective Cohort Study
Ma Sheryll R De Jesus
University of the Philippines, Philippines
Objective:
To determine the risk of postpartum hemorrhage among patients who were treated with nifedipine for tocolysis of
preterm labor.
Study design:
A prospective cohort study was conducted with 66 pregnant women admitted for preterm labor. One group of women
was given nifedipine to give time for the administration of corticosteroids for fetal lung maturity and/or control of preterm labor and
one group was not given with nifedipine as they were admitted at far advanced stage of labor. Independent/Paired Sample T-test,
Mann-Whitney U/Wilcoxon Signed rank test and Fisher’s exact test were used to determine the difference of mean, median and
frequency between and within groups, respectively. STATA 12.0 was used for data analysis.
Results:
There was more blood loss during delivery among those who received nifedipine compared to those who have not taken
the medicine, which was statistically significant (350 ml versus 250 ml, p=0.021). Furthermore, the decreases in hemoglobin and
hematocrit were also lower among those who did not receive nifedipine compared to those who received nifedipine for tocolysis (8.5
mg/dL versus 16.0 mg/dL, p=0.014 and 0.03 versus 0.05, p= 0.010), again, statistically significant.
Conclusion:
Nifedipine used as tocolytic appear to increase blood loss during delivery, which was statistically significant. Greater
amount of blood loss may be anticipated among those with nifedipine intake thus helping the obstetrician in preparing for active
management of postpartum hemorrhage and preventing maternal morbidity and mortality.
Biography
DR. MA. SHERYLL R. DE JESUS finished her residency training in Obstetrics and Gynecology at the University of the Philippines – Philippine General Hospital in
2016. She is currently a Fellow-in-Training at the Section of Reproductive Endocrinology and Infertility at the same institution. She plans to pursue her career and
study in-vitro fertilization in the future.
she_deejhay_07@yahoo.comMa Sheryll R De Jesus, Gynecol Obstet (Sunnyvale) 2017, 7:10(Suppl)
DOI: 10.4172/2161-0932-C1-021