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Gastro 2016
August 11-12, 2016
Volume 6, Issue 4(Suppl) J Gastrointest Dig Syst 2016
ISSN:2161-069X JGDS, an open access journal
conferenceseries .com
August 11-12, 2016 Birmingham, UK
6th Global Gastroenterologists Meeting
EslamAhmed Habba, J Gastrointest Dig Syst 2016, 6:4(Suppl)
Seronegative autoimmune hepatitis in children: A report of a rare case in Egyptian community
Eslam Ahmed Habba
Tanta Faculty of Medicine, Egypt
Background: Autoimmune hepatitis is seen in all the ages and races. The general principles of diagnosis and management of
AIH presenting in childhood are similar to those presented in adult patients with some caveats. More than 50% of children
will have evidence of cirrhosis and the milder forms are not usually seen, this justifies initiation of early treatment following
diagnosis.
Case: A 4 year old boy was presented with jaundice and abdominal enlargement especially on the right hypochondrium. On
physical examination it was found that there was a hepatomegaly about 10 cm below right costal margin and jaundice. CBC,
liver function tests, serum markers for HAV, HBV, HCV, AIH, hemochromatosis, Wilson disease and primary biliary cirrhosis
were not conclusive except positive HAV IgM lasting for more than a year and rising ALT & AST up to 1113 IU/ml. Biopsy
was done which revealed a picture of severe autoimmune hepatitis with incipient cirrhosis. Immunosuppressive therapy was
started with marvelous treatment response and resolution of the severe hepatitis.
Conclusion: AIH is a rare liver disease that can be presented aggressively in children. Early treatment can control the hyper
immune state and save the liver.
Biography
Eslam Ahmed Habba is an Assistant Lecturer of Hepatology, Gastroenterology And Infectious Diseases at Tropical Medicine Department, Faculty of Medicine,
Tanta University Hospitals, Egypt. He is an active member of European Association for the Study of the Liver (EASL). Also, he is a Member of American Association
for Study of Liver Diseases (AASLD) and a Member of Liver Tumors Committee at New Tanta Universal Teaching Hospitals. He has some published papers in the
field of hepatology and infections. Recently, he had a published book about hepatocellular carcinoma available online and everywhere. He was granted an EASL
membership for the year 2016 after his research poster was awarded in EASL monothematic conference in Romania in 2015.