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Volume 09 Journal of Gastrointestinal & Digestive System
ISSN: 2161-069X Gastro Congress 2019
July 08-09, 2019
July 08-09, 2019 | Zurich, Switzerland
14th Euro-Global Gastroenterology Conference
Relevance of proton pump inhibitors prescriptions in the hospital setting in Lebanon
Rami George Maalouf
Holy Spirit University of Kaslik, Lebanon
Statement of the Problem: Studies have shown that PPIs are frequently used in an inappropriate way, above the
standard doses and against the recommendations, leading to adverse events likemalabsorption problems, community
acquired pneumonia, hip fractures and Clostridium difficile colitis. In Lebanon only one study about the out-patient
use of PPI was done in community pharmacies, but in-patient prescription studies are inexistent. Our study will
evaluate the use of PPIs in a hospital setting in Lebanon and will compare it to international recommendations.
Methodology & Theoretical Orientation: Cross-sectional study, conducted in a university hospital in Lebanon
(CHU NDS) between June and November 2018, included 186 randomly selected Lebanese inpatient adults.
Findings: Less than half of the participants (46.8%) received a PPI for the adequate indication and 83.9% received
the adequate PPI molecule, whereas only 9.2% received the adequate dose. The rate of PPI misuse was higher in
the surgery ward (59.6%) than in the medicine department (40.4%) (Cardiology, internal medicine, neurology,
pneumology, nephrology, infectious diseases, gastro-enterology and rheumatology). Concerning age, 56.3% of
the ≥65 year’s old patients were taking PPI for the right indication. However, among those who are <65 years old,
only 43.7% of the prescriptions were recommended. Also adequate PPI indication and adequate choice of drug was
mainly noticed in patients having GI history or taking antiplatelet therapy.
Conclusion: Our study has shown that a significant amount of PPIs was prescribed inadequately leading to a need
to re-evaluate or adjust the use of PPIs among Lebanese physicians.
J Gastrointest Dig Syst 2019, Volume 09