euro-toxicology-2016_scientifictracks-abstracts

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Volume 6, Issue 6(Suppl) J Clin Toxicol 2016
ISSN: 2161-0495, JCT an open access journal
Page 130
Notes:
Euro Toxicology 2016
October 24-26, 2016
conferenceseries.com
Toxicology & Applied Pharmacology
October 24-26, 2016 Rome, Italy
7th Euro-Global Summit on
Determination of chromium by ETAAS in hair and urine of tannery workers: The interest of
alternative biological matrices
Mohammed Riffi1, Okacha Abdelmalek1, Rania Abtroun1, Mohammed Azzouz 2, Mohammed Reggabi2 and Barkahoum Alamir1,3
1CHU Bab el Oued, Algeria
2Biologie Toxicology Laboratory, Algeria
3National Center of toxicology, NIP, Algeria
Introduction: The human hair occupies a prominent place as markers of exposure to xenobiotics in the domain of forensic
toxicology. However, interest of using this matrix is a considerable improvement for the assay of metals; also, chromium has
attracted the attention of toxicologists because the accidents observed in industrial settings using this metallic element (cement
industry, paint, leather, automotive, etc.).
Objective: This study is related to the assessment of worker exposure in a tannery, located in Algiers, more accurately on the
Rouiba-Reghaia industrial estate, by measuring the capillary and urinary chromium of the population groups investigated, and
then study the correlation between total content of chromium in hair and urine.
Patients &Methods: The study was carried out in September 2012, and focused on 50 subjects exposed (49 men and 1 woman)
and 16 controls. It was preceded by the establishment analytical development and validation of an analytical method for
the determination of chromium in hair and urine by graphite furnace atomic absorption spectrometry (GFAAS). Statistical
calculations were performed using the software LXSTAT MS Excel 2012.
Results & Discussion: The hair chromium average of the tanning workers were significantly higher (urinary Cr=2.48 μg/L,
Cr capillary=4.93 ng/mg) than other groups. Washing the hair appears to be effective for decontaminating the exogenous
chromium, this latter may reflect a recent exposure to chromium.
Conclusion: Human hair may offer the advantage for biological monitoring, first, to get information on the use of means of
protection, and give some idea about the route of exposure (inhalation or ingestion).
Biography
Mohammed Riffi has completed his PhD from Tlemcen University and Post-doctoral studies from Algiers University School of Medicine. He has a membership of
SoHT. He has published one paper in Toxicologie analytique et Clinique.
Mohammed Riffi et al., J Clin Toxicol 2016, 6:6(Suppl)