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Volume 6, Issue 6(Suppl)

J Clin Toxicol 2016

ISSN: 2161-0495, JCT an open access journal

Page 74

Notes:

Euro Toxicology 2016

October 24-26, 2016

conferenceseries

.com

Toxicology & Applied Pharmacology

October 24-26, 2016 Rome, Italy

7

th

Euro-Global Summit on

Coal-burning type of endemic fluorosis in China – From basic research to clinic prevention

Zhi-Zhong Guan

Guizhou Medical University, P R China

E

ndemic fluorosis widely occurs in the world and is characterized by skeletal and dental fluorosis and a vast array of

pathological changes in whole bodies, which has been proved by our large number of basic investigations. Coal-burning

type of endemic fluorosis is the severest one, which was confirmed in China in 1970’s. This type of endemic fluorosis is primarily

induced by fluoride-contaminated food and air indoor caused by smoke emitted during burning coal, which contains a high

concentration of fluoride. In China, about 36 millions of people live in such areas of coal-burning type of endemic flruosis.

Among the population, 18 millions are suffered from dental fluorosis and 1.5 millions skeletal fluorosis. Since 1980, an efficient

strategy relating integrated control has been carried out for eliminating the disease in in China. After taking the measurement

for many years, the adapted coal-burning stoves have been set up and the improve health education obtained in most of

families in the endemic fluorosis areas, which brings the significant decline of fluoride contamination on food and air indoor.

The strategy has successfully resulted in a significant decrease in the numbers of the patients with dental and skeletal fluorosis,

and in a great improvement in health conditions of the people lived in the areas. At present, the coal-burning type of endemic

fluorosis in China has been efficiently controlled at present. Importantly, it is necessary to take a long-period of integrated

control for efficiently eliminating the hazard of coal-burning type of endemic fluorosis.

Biography

Zhi-Zhong Guan completed his PhD from Karolinska Institutet, Sweden in 1997. He is the Director of the Key Lab of the Endemic and Ethnic Diseases in Education

Ministry of China. He has published more than 400 papers (including more than 100 SCI collected papers) in peer-reviewed journals and has been serving as an

Editorial Board Member or reviewer of several journals.

1457658298@qq.com

Zhi-Zhong Guan, J Clin Toxicol 2016, 6:6(Suppl)

http://dx.doi.org/10.4172/2161-0495.C1.021