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conferenceseries
.com
Volume 7, Issue 4 (Suppl)
J Clin Exp Pathol, an open access journal
ISSN: 2161-0681
Euro Pathology 2017
August 02-03, 2017
13
th
EUROPEAN PATHOLOGY CONGRESS
August 02-03, 2017 Milan, Italy
Multimodal
in vivo
imaging strategies for early cancer diagnostics
Tomasz S Tkaczyk
Rice University, USA
M
onitoring and diagnostics of many cancers like oral, cervical or esophageal adenocarcinoma often require multimodal
approach toperformsuccessful diagnostics. Bothmorphological imaging and spectral assessment are important tools used
in these applications. When, used separately, either method cannot easily achieve both high sensitivity and specificity
in vivo
.
On the other hand, if combined and working in tandem, they can significantly improve the diagnostic performance. Therefore,
this presentation focuses on analysis of multimodal approaches/instrumentation for early
in vivo
cancer detection. Two
groups of devices will be discussed: Miniature-integrated imaging microscopes (endomicroscopes) to provide morphological
content and multi and hyperspectral high speed systems to obtain bio-chemical signatures of the tissue. Practical aspects of
multi-modal system integration, performance and parameters (field of view and resolution of individual sub-systems) will be
discussed together with the design considerations to optimize its effectiveness. Number of imaging methods will be presented
including (for morphological assessment): Contact imaging, confocal, structure illumination, and multi-photon imaging and
(in area of spectral detection) narrow band imaging (NBI), image mapping spectrometry IMS, array snapshot systems in
number of cancer applications (including for example oral, cervical, and esophageal adenocarcinoma).
Biography
Tomasz S Tkaczyk received his MS and PhD degrees at Institute of Micromechanics and Photonics, Warsaw University of Technology. Currently, he is an Associate
Professor of Bioengineering and Electrical and Computer Engineering at Rice University. He joined Rice University in 2007 after his research at University of
Arizona. His research interest includes “Microscopy, endoscopy/
in vivo
pathology, point of care systems, and spectroscopy”. He has published 60+ per-reviewed
communications. He is a fellow of OSA and SPIE, and recipient of number of professional awards including Paul F. Forman Engineering Excellence Award (OSA),
Becton Dickinson Professional Achievement Award (AAMI).
ttkaczyk@rice.eduTomasz S Tkaczyk, J Clin Exp Pathol 2017, 7:4(Suppl)
DOI: 10.4172/2161-0681-C1-037